{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,27]],"date-time":"2025-09-27T21:55:28Z","timestamp":1759010128463,"version":"3.40.5"},"reference-count":13,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2022,9,20]],"date-time":"2022-09-20T00:00:00Z","timestamp":1663632000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Cosmetic Dermatology"],"published-print":{"date-parts":[[2022,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>The impact of psoriasis on the outcomes of Coronavirus disease 2019 (COVID\u201019) is yet to be precisely delineated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To assess the risk of COVID\u201019, COVID\u201019\u2010associated hospitalization, and mortality among patients with psoriasis as compared with age\u2010, sex\u2010, and ethnicity\u2010matched control subjects. In addition, we aim to delineate determinants of COVID\u201019\u2010associated hospitalization and mortality in patients with psoriasis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A population\u2010based retrospective cohort study was performed to longitudinally follow patients with psoriasis and their matched controls with regard to COVID\u201019\u2010related outcomes. The risk of COVID\u201019 infection, COVID\u201019\u2010associated hospitalization, and mortality were assessed using uni\u2010 and multi\u2010variable Cox regression analyses. Determinants of COVID\u201019\u2010associated hospitalization and mortality were evaluated using multivariable logistic regression analysis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The study population included 144\u2009304 patients with psoriasis and 144\u2009304 age\u2010 and sex\u2010matched control individuals. Patients with psoriasis displayed a slightly elevated risk of SARS\u2010CoV\u20102 infection (fully\u2010adjusted HR, 1.05; 95% CI, 1.03\u20131.08; <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001). Relative to controls, patients with psoriasis had comparable multivariate risk of COVID\u201019\u2010associated hospitalization (fully\u2010adjusted HR, 1.08; 95% CI, 0.99\u20131.18; <jats:italic>p<\/jats:italic>\u00a0=\u00a00.065) and COVID\u201019\u2010associated mortality (fully\u2010adjusted HR, 0.88; 95% CI, 0.73\u20131.05; <jats:italic>p<\/jats:italic>\u00a0=\u00a00.162). When evaluating individuals hospitalized due to COVID\u201019, patients with psoriasis were more likely to have type\u20102 diabetes mellitus (adjusted OR, 1.24; 95% CI, 1.03\u20131.50; <jats:italic>p<\/jats:italic>\u00a0=\u00a00.027) and obesity (adjusted OR, 1.37; 95% CI, 1.13\u20131.65; <jats:italic>p<\/jats:italic>\u00a0=\u00a00.001) relative to controls.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>While patients with psoriasis are at a higher risk of contracting SARS\u2010CoV\u20102 infection, they are not more susceptible to the complications of COVID\u201019.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jocd.15351","type":"journal-article","created":{"date-parts":[[2022,9,3]],"date-time":"2022-09-03T10:37:53Z","timestamp":1662201473000},"page":"6549-6553","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Nineteen months into the pandemic, what have we learned about <scp>COVID<\/scp>\u201019\u2010related outcomes in patients with psoriasis?"],"prefix":"10.1111","volume":"21","author":[{"given":"Khalaf","family":"Kridin","sequence":"first","affiliation":[{"name":"Unit of Dermatology and Skin Research Laboratory Baruch Padeh Poria Medical Center  Tiberias Israel"},{"name":"Azrieli Faculty of Medicine Bar\u2010Ilan University  Safed Israel"},{"name":"L\u00fcbeck Institute of Experimental Dermatology University of L\u00fcbeck  L\u00fcbeck Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yochai","family":"Schonmann","sequence":"additional","affiliation":[{"name":"Clalit Health Services  Tel\u2010Aviv Israel"},{"name":"Faculty of Health Sciences Ben\u2010Gurion University of the Negev  Beer Sheva Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Erez","family":"Onn","sequence":"additional","affiliation":[{"name":"Azrieli Faculty of Medicine Bar\u2010Ilan University  Safed Israel"},{"name":"Baruch Padeh Medical Center  Poriya Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dana Tzur","family":"Bitan","sequence":"additional","affiliation":[{"name":"Department of Behavioral Sciences Ariel University  Ariel Israel"},{"name":"Shalvata Mental Health Center, Hod Hasharon, affiliated with the Sackler School of Medicine Tel Aviv University  Ramat Aviv Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Orly","family":"Weinstein","sequence":"additional","affiliation":[{"name":"Clalit Health Services  Tel\u2010Aviv Israel"},{"name":"Faculty of Health Sciences Ben\u2010Gurion University of the Negev  Beer Sheva Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2397-6316","authenticated-orcid":false,"given":"Eran","family":"Shavit","sequence":"additional","affiliation":[{"name":"Dermatology Clinic Wolfson Medical Center  Holon Israel"},{"name":"The Sackler faculty of Medicine Tel\u2010Aviv University  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