{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T01:12:27Z","timestamp":1787015547887,"version":"build-2736575974"},"reference-count":13,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2022,10,12]],"date-time":"2022-10-12T00:00:00Z","timestamp":1665532800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Cosmetic Dermatology"],"published-print":{"date-parts":[[2022,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Acne lesion counting (ALC) is widely used to evaluate efficacy of new acne treatments. Although such evaluations are precise and highly discriminative, if assessed live, it can be a time\u2010consuming and intrusive measurement. Photographic assessment is a viable mode for ALCs and for training and\/or qualifying evaluators.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>The purpose of this study was to validate photographic methods for performing ALCs and to provide an objective measurement tool to train and\/or qualify lesion count evaluators for deployment in both small\u2010 and large\u2010scale studies.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Patients\/Methods<\/jats:title>\n                    <jats:p>Assess accuracy and reliability of acne lesion counting via photographic methods in 8 subjects aged 16 to 40\u2009years, with Fitzpatrick Skin Types I to VI. Frontal and 45\u00b0angle images taken at the single in\u2010clinic visit. Each subject underwent 3 counts per 4 evaluators: 1 set of live counts and 2 sets of photo counts. Intra\u2010evaluator and inter\u2010evaluator reliability measures for photo counts were evaluated using calculations of intraclass correlation coefficients (ICCs).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Eight subjects (2 males and 6 females) age between 16 and 40 (min 16\u2009years, max 25\u2009years) diagnosed with facial acne vulgaris participated in the study. Fitzpatrick Skin Types ranged from III to V (three Type\u2010III, four Type\u2010IV, and one Type\u2010V). ICC values for intra\u2010evaluator reliability were found to be &gt;0.95 for each evaluator, and ICC for inter\u2010evaluator reliability was found to be 0.98.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Photographic lesion count methodology is a reliable and accurate tool for objective measurement of ALCs and additionally, for training and\/or qualifying evaluators.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jocd.15413","type":"journal-article","created":{"date-parts":[[2022,9,26]],"date-time":"2022-09-26T10:30:58Z","timestamp":1664188258000},"page":"6965-6975","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Picture\u2010based acne lesion counts: A validation study to assess accuracy and reliability of acne lesion counts via photography"],"prefix":"10.1111","volume":"21","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5183-5433","authenticated-orcid":false,"given":"Michael H.","family":"Gold","sequence":"first","affiliation":[{"name":"Gold Skin Care Center  Nashville Tennessee USA"},{"name":"Tennessee Clinical Research Center  Nashville Tennessee USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ashish","family":"Bhatia","sequence":"additional","affiliation":[{"name":"Oak Dermatology  Naperville Illinois USA"},{"name":"Feinberg School of Medicine Northwestern University  Chicago Illinois USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arshdeep","family":"Kaur","sequence":"additional","affiliation":[{"name":"Cutera, Inc.  Brisbane California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Margot","family":"Doucette","sequence":"additional","affiliation":[{"name":"Cutera, Inc.  Brisbane California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amogh","family":"Kothare","sequence":"additional","affiliation":[{"name":"Cutera, Inc.  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