{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T02:38:11Z","timestamp":1790735891829,"version":"4.1.0"},"reference-count":24,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2022,10,31]],"date-time":"2022-10-31T00:00:00Z","timestamp":1667174400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100004484","name":"Tehran University of Medical Sciences and Health Services","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004484","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Cosmetic Dermatology"],"published-print":{"date-parts":[[2022,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Among several surgical treatments, the use of transplantation of epidermal cultured melanocytes or melanocytes\u2013keratinocytes cell suspension has gained many researchers and dermatologists' attention as a new technique for the treatment of vitiligo. The present study aimed to transplant autologous epidermal melanocytes\u2013keratinocytes cell suspension for the treatment of vitiligo.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>In this study, 15 volunteer patients aged between 18 and 45\u2009years old were studied. The autologous melanocytes\u2013keratinocytes cell suspension was then transplanted to the region after dermabrasion. The included patients were evaluated by VisioFace, MPA9, and Skin Scanner\u2010DUB once before and 1, 2, and 6\u00a0months after the transplantation, while the extents of stainability and changes in the transplanted region were recorded.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The color contrast between the lesion and normal skin significantly decreased after 1, 2, and 6\u00a0months of the melanocytes transplantation compared with the pre\u2010procedure (13.8\u2009\u00b1\u20090.45 before vs. 12.9\u2009\u00b1\u20090.43, 12.2\u2009\u00b1\u20090.45, and 10.2\u2009\u00b1\u20090.34 at months 1, 2, and 6,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). Furthermore, melanin index significantly increased six months after cell transplantation compared to the pretreatment (168.3\u2009\u00b1\u20094.22 vs. 130.5\u2009\u00b1\u20093.98,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Transplantation of melanocytes cells with dermabrasion can be effective on vitiligo improvement, so it is recommended.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jocd.15423","type":"journal-article","created":{"date-parts":[[2022,10,8]],"date-time":"2022-10-08T02:43:04Z","timestamp":1665196984000},"page":"7147-7152","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Transplantation of autologous epidermal melanocyte\u2013keratinocyte cells suspension for cell therapy of vitiligo: A\u00a0clinical evaluation and biometric assessment"],"prefix":"10.1111","volume":"21","author":[{"given":"Mohammad Ali","family":"Nilforoushzadeh","sequence":"first","affiliation":[{"name":"Skin and Stem Cell Research Center Tehran University of Medical Sciences  Tehran Iran"},{"name":"Skin Repair Research Center Jordan Dermatology and Hair Transplantation Center  Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0575-4381","authenticated-orcid":false,"given":"Susan","family":"Farshi","sequence":"additional","affiliation":[{"name":"Skin and Stem Cell Research Center Tehran University of Medical Sciences  Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1267-3232","authenticated-orcid":false,"given":"Maryam","family":"Nouri","sequence":"additional","affiliation":[{"name":"Skin and Stem Cell Research Center Tehran University of Medical Sciences  Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shiva","family":"Alavi","sequence":"additional","affiliation":[{"name":"Skin and Stem Cell Research Center Tehran University of Medical Sciences  Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Batool","family":"Bayat Tork","sequence":"additional","affiliation":[{"name":"Skin and Stem Cell Research Center Tehran University of Medical Sciences  Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fariba","family":"Jaffary","sequence":"additional","affiliation":[{"name":"Skin Diseases and Leishmaniasis Research Center Isfahan University of Medical Sciences  Isfahan Iran"},{"name":"Medical Education Research Center Isfahan University of Medical Sciences  Isfahan 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