{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T03:21:31Z","timestamp":1782184891884,"version":"3.54.5"},"reference-count":27,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2022,11,8]],"date-time":"2022-11-08T00:00:00Z","timestamp":1667865600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003710","name":"Korea Health Industry Development Institute","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003710","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Cosmetic Dermatology"],"published-print":{"date-parts":[[2023,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Photobiomodulation therapy (PBMT) appears to be safe and effective for hair loss. Pulsed electromagnetic field therapy (PEMF) also has a positive biological effect on hair re\u2010growth.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>We evaluated the efficacy and safety of both PBMT and PEMF for the treatment of androgenetic alopecia (AGA).<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>This study was a 24\u2010week, randomized, double\u2010blind, sham device\u2010controlled trial. We recruited 80 subjects with androgenetic alopecia. The subjects got treatment every week for the 1st 12\u2009weeks, every other week for the next 8\u2009weeks. PBMT entails 15\u2010min therapy, and PEMF was carried out for 10\u00a0min.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The baseline hair density was 114.57 (\u00b128.75)\/cm<jats:sup>2<\/jats:sup> and 113.31 (\u00b130.07)\/cm<jats:sup>2<\/jats:sup> in both treatment and control groups. After 24\u2009weeks of treatment, the mean hair density increased to 139.37 (\u00b131.4)\/cm<jats:sup>2<\/jats:sup> in the treatment group but only to 119.78 (\u00b131.92)\/cm<jats:sup>2<\/jats:sup> in the control group. The difference between two groups was statistically significant (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.05). Based on the global assessment of independent experts, the score was 0.41 (\u00b10.62) in the treatment group and 0.07 (\u00b10.45) in the control group. Only very mild erythema or irritation was reported, and no serious adverse reactions were reported.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>A combination of PBMT and PEMF is a valid and safe treatment option for AGA.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jocd.15490","type":"journal-article","created":{"date-parts":[[2022,11,8]],"date-time":"2022-11-08T10:44:29Z","timestamp":1667904269000},"page":"831-836","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["The efficacy and safety of the combination of photobiomodulation therapy and pulsed electromagnetic field therapy on androgenetic alopecia"],"prefix":"10.1111","volume":"22","author":[{"given":"Mi Soo","family":"Choi","sequence":"first","affiliation":[{"name":"Department of Dermatology Dankook University Hospital  Cheonan Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Byung Cheol","family":"Park","sequence":"additional","affiliation":[{"name":"Department of Dermatology Dankook University Hospital  Cheonan Republic of Korea"},{"name":"Beckman Laser Institute Korea, Cheonan Campus, Dankook University  Cheonan Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,11,8]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2017.02.054"},{"issue":"5","key":"e_1_2_8_3_1","first-page":"312","article-title":"Low\u2010intensity laser therapy: a review","volume":"48","author":"Schindl A","year":"2000","journal-title":"J Invest Med"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.15081"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/dsu.12200"},{"key":"e_1_2_8_6_1","first-page":"628","article-title":"Influence of laser beams on the growth of hair in mice","volume":"19","author":"Mester 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