{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T03:23:17Z","timestamp":1793157797840,"version":"4.5.0"},"reference-count":19,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2022,11,29]],"date-time":"2022-11-29T00:00:00Z","timestamp":1669680000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Cosmetic Dermatology"],"published-print":{"date-parts":[[2023,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Botulinum toxin A (BoNTA) treatments are popular worldwide. Young adults, less than 41\u2009years of age, are an important cohort of patients seen in practice, and the optimal dosage of BoNTA in this age group remains poorly defined.<\/jats:p><\/jats:sec><jats:sec><jats:title>Aims and Objective<\/jats:title><jats:p>To determine the optimal dosing of BoNTA across different age\u2010matched cohorts by reviewing the literature and to evaluate current BoNTA practices among aesthetic practitioners when treating younger versus older adults.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>An evidence\u2010based literature review was performed to evaluate the current evidence on BoNTA injections for cosmetic indications in millennials (born between 1981 and 1996) and young adults. A cross\u2010sectional online survey was distributed to aesthetic practitioners to assess their current practice with BoNTA.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>There is a paucity of high\u2010quality research on BoNT in millennials. Our literature review suggests different patterns of practice when treating younger adults. Specifically, our survey revealed that: (1) younger adults are receiving, on average, fewer units of BoNTA at the glabella, forehead, and crow's feet, (2) younger toxin\u2010na\u00efve patients are also afraid to look frozen or unnatural, and (3) wrinkles prevention was the most common reason for seeking treatment in younger patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The literature review supports the efficacy of BoNTA for correcting wrinkles in millennials. Our findings provide further insight into the dosing pattern of cosmetic BoNTA and motivating factors for seeking treatments in young adults. This valuable information will help practitioners with treatment planning when seeing patients from different age cohorts. An individualized approach and a lower dosage of BoNTA in toxin\u2010na\u00efve younger adults are recommended.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jocd.15513","type":"journal-article","created":{"date-parts":[[2022,11,29]],"date-time":"2022-11-29T18:10:33Z","timestamp":1669745433000},"page":"128-139","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":27,"title":["Botulinum toxin for cosmetic treatments in young adults: An evidence\u2010based review and survey on current practice among aesthetic practitioners"],"prefix":"10.1111","volume":"22","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2907-4746","authenticated-orcid":false,"given":"Alain","family":"Michon","sequence":"first","affiliation":[{"name":"The Ottawa Skin Clinic\/Project Skin MD Ottawa  Ottawa Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,11,29]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0036-1582234"},{"key":"e_1_2_9_3_1","volume-title":"Changing the Body: Psychological Effects of Plastic Surgery","author":"Goin JM","year":"1981"},{"key":"e_1_2_9_4_1","unstructured":"Statisa.Consumers puchasing skinc care the most amont all beauty categories in the United States in 2021 USA.2021. 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