{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T18:57:11Z","timestamp":1780426631697,"version":"3.54.1"},"reference-count":24,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2022,11,27]],"date-time":"2022-11-27T00:00:00Z","timestamp":1669507200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Cosmetic Dermatology"],"published-print":{"date-parts":[[2023,3]]},"abstract":"Abstract<\/jats:title>Background<\/jats:title>Of the many effects induced by UV radiation on the skin, erythema is one of the most well\u2010known features, which is a cutaneous inflammatory reaction correlated with acute photodamage. The utilization of sunscreen may reduce this process.<\/jats:p><\/jats:sec>Aims<\/jats:title>To evaluate the utilization of a sunscreen SPF50 with high antioxidant capacity during 15\u2009days by young men without photoprotection habits.<\/jats:p><\/jats:sec>Methods<\/jats:title>For this, we evaluated erythema, skin hydration properties, and dermis echogenicity using skin imaging techniques. Forty male participants (aged between 18 and 28\u2009years old), 36 without previous photoprotection habits, were recruited, and the erythema was evaluated using a visual score and skin colorimeter. Macroscopic images (VivaCam\u00ae) were also obtained. Dermis echogenicity was evaluated using high\u2010frequency ultrasonography. All the participants received a sunscreen SPF 50 to use for 15\u2009days.<\/jats:p><\/jats:sec>Results<\/jats:title>The visual score presented a strong correlation (r<\/jats:italic>\u00a0=\u00a00.8657) with the colorimeter results. Visually and using the biophysical methodologies was possible to observe the reduction of the visual erythema. The dermis echogenicity also improved, probably correlated with the acute inflammation reduction. No alterations were observed in the skin hydration and skin barrier parameters.<\/jats:p><\/jats:sec>Conclusions<\/jats:title>The utilization of complementary and correlated different skin biophysical and imaging techniques in this study allows a better comprehension regarding the skin early photoaging process due the direct sun exposure. The utilization with a SPF 50 sunscreen with high antioxidant potential allows for a reduction in the erythema after 15\u2009days of usage, a quick result, however, did not improved the skin barrier or SC hydration.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jocd.15528","type":"journal-article","created":{"date-parts":[[2022,11,28]],"date-time":"2022-11-28T07:17:52Z","timestamp":1669619872000},"page":"872-879","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Applying sunscreen SPF<\/scp> 50 with high antioxidant capacity during fifteen days improves the dermis echogenicity and reduces the reddish skin undertone"],"prefix":"10.1111","volume":"22","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7151-5755","authenticated-orcid":false,"given":"Victor Hugo Pacagnelli","family":"Infante","sequence":"first","affiliation":[{"name":"School of Pharmaceutical Sciences of Ribeir\u00e3o Preto University of S\u00e3o Paulo Ribeirao Preto Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6678-1207","authenticated-orcid":false,"given":"Patr\u00edcia Maria Berardo Gon\u00e7alves","family":"Maia Campos","sequence":"additional","affiliation":[{"name":"School of Pharmaceutical Sciences of Ribeir\u00e3o Preto University of S\u00e3o Paulo Ribeirao Preto Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,11,27]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdermsci.2016.09.015"},{"issue":"3","key":"e_1_2_9_3_1","first-page":"1345","article-title":"Biological effects of sunlight, ultraviolet radiation, visible light, infrared radiation and vitamin D for health","volume":"36","author":"Holick MF","year":"2016","journal-title":"Anticancer 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