{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T02:11:28Z","timestamp":1790993488869,"version":"4.1.0"},"reference-count":64,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100015549","name":"Science and Technology Development Fund","doi-asserted-by":"publisher","award":["21ZYTS01"],"award-info":[{"award-number":["21ZYTS01"]}],"id":[{"id":"10.13039\/100015549","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Cosmetic Dermatology"],"published-print":{"date-parts":[[2023,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Vitiligo was an autoimmune disease and some guidelines for the management of vitiligo encouraged the use of NB\u2010UVB combination therapies to enhance repigmentation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To compare the effectiveness of current NB\u2010UVB combination regimen at the improvement in repigmentation through a systematic review and network meta\u2010analysis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We searched the electronic databases for randomized controlled trials related to NB\u2010UVB combination therapy for vitiligo till October 2022. STATA15.0 software was applied to carrying out data analysis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 28 eligible studies involving 1194 participants were enrolled in the analysis. The NMA results revealed that compared with NB\u2010UVB, carboxytherapy [OR\u00a0=\u00a032.35, 95% CI (1.79, 586.05)], Er: YAG laser+ topical 5% 5\u2010FU [OR\u00a0=\u00a010.74, 95% CI (4.05, 28.49)], needling\/micro\u2010needling [OR\u00a0=\u00a03.42, 95% CI (1.18, 9.88)], betamethasone intramuscular injection [OR\u00a0=\u00a03.08, 95% CI (1.17, 8.13)], topical tacrolimus [OR\u00a0=\u00a02.54, 95% CI (1.30, 4.94)], and oral Chinese herbal medicine compound [OR\u00a0=\u00a02.51, 95% CI (1.40, 4.50)] integrated with NB\u2010UVB were more efficacious in excellent to complete repigmentation response rate (\u226575%). Besides, NB\u2010UVB+ Er: YAG laser+ topical 5% 5\u2010FU [OR\u00a0=\u00a00.17, 95% CI (0.04, 0.67)] and NB\u2010UVB+ needling\/micro\u2010needling [OR\u00a0=\u00a00.24, 95% CI (0.06, 0.88)] were less likely evaluated as ineffective repigmentation response (\u226425%).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>All combination therapies ranked higher than NB\u2010UVB monotherapy in inducing successful repigmentation and avoiding failed treatment in patients with vitiligo. Comprehensive consideration, NB\u2010UVB+ Er: YAG laser+ topical 5% 5\u2010FU and NB\u2010UVB+ needling\/microneedling would be the preferred therapeutic approaches.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jocd.15534","type":"journal-article","created":{"date-parts":[[2022,12,2]],"date-time":"2022-12-02T07:30:53Z","timestamp":1669966253000},"page":"1083-1098","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":26,"title":["Comparison of <scp>NB\u2010UVB<\/scp> combination therapy regimens for vitiligo: A systematic review and network <scp>meta\u2010analysis<\/scp>"],"prefix":"10.1111","volume":"22","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0985-796X","authenticated-orcid":false,"given":"Baohua","family":"Zhu","sequence":"first","affiliation":[{"name":"Hospital of Chengdu University of Traditional Chinese Medicine  Chengdu 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