{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T21:55:40Z","timestamp":1791842140916,"version":"4.3.4"},"reference-count":20,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2022,12,28]],"date-time":"2022-12-28T00:00:00Z","timestamp":1672185600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Cosmetic Dermatology"],"published-print":{"date-parts":[[2023,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Selective photothermolysis on sebaceous glands is an effective method for treating acne vulgaris (AV); however, safety, efficacy, and discomfort hinder its utilization in clinical settings.<\/jats:p><\/jats:sec><jats:sec><jats:title>Aims<\/jats:title><jats:p>The primary objective is to evaluate the safety and efficacy of a novel 1726\u2009nm laser with contact cooling to treat AV.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Seventeen patients aged 18 to 36 were enrolled and treated in this IRB\u2010approved, single\u2010center, open\u2010label study. Patients received up to three facial laser sessions up to seven weeks apart. Follow\u2010up visits happened ten days post\u2010session and at the 4 and 12\u2009weeks following the final session. The investigator assessed the severity of device\u2010related adverse events (AEs). Investigator Global Assessment (IGA) and inflammatory lesion counts (ILC) were used as metrics to evaluate acne resolution and skin condition enhancement. Patients' perspectives on satisfaction and comfort using this technology were assessed using Subject Experience Questionnaires (SEQ).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Safety assessment showed mild and transient AEs. All subjects tolerated anesthetics\u2010free treatments well, with a mean treatment discomfort score of 4.9\u00a0\u00b1\u20091.5. Compared to baseline, a statistically significant reduction in ILC (<jats:italic>p\u00a0=\u00a00.003<\/jats:italic>) of 52% to 56% is achieved four to twelve weeks following treatment. Long\u2010term follow\u2010ups showed progressive improvement 24\u2009months post\u2010treatment with a 97% reduction in ILC. SEQs revealed high subject satisfaction (71%) with psychosocial improvement three months post\u2010treatment.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The novel 1726\u2009nm laser appears safe and effective for treating mild\u2010to\u2010severe acne. Acne resolution is apparent within the first month and progresses beyond the study duration.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jocd.15602","type":"journal-article","created":{"date-parts":[[2022,12,28]],"date-time":"2022-12-28T17:37:51Z","timestamp":1672249071000},"page":"486-496","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":32,"title":["Selective photothermolysis with a novel 1726 nm laser beam: A safe and effective solution for acne vulgaris"],"prefix":"10.1111","volume":"22","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1465-0691","authenticated-orcid":false,"given":"David","family":"Goldberg","sequence":"first","affiliation":[{"name":"Dermatology Icahn School of Medicine at Mt. Sinai  New York New York City USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amogh","family":"Kothare","sequence":"additional","affiliation":[{"name":"Cutera, Inc.  California Brisbane USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Margot","family":"Doucette","sequence":"additional","affiliation":[{"name":"Cutera, Inc.  California Brisbane USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arshdeep","family":"Kaur","sequence":"additional","affiliation":[{"name":"Cutera, Inc.  California Brisbane USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephen","family":"Ronan","sequence":"additional","affiliation":[{"name":"Blackhawk Plastic Surgery and MedSpa  California Danville USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeffrey","family":"Fromowitz","sequence":"additional","affiliation":[{"name":"Dermatology Schmidt College of Medicine, Florida Atlantic University  Florida Boca Raton USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9398-8502","authenticated-orcid":false,"given":"Amer","family":"Hamidi\u2010Sakr","sequence":"additional","affiliation":[{"name":"Cutera, Inc.  California Brisbane USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,12,28]]},"reference":[{"key":"e_1_2_10_2_1","first-page":"978","article-title":"Psychological sequelae of acne vulgaris","volume":"52","author":"Magin P","year":"2006","journal-title":"Can Fam Physician"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1503\/cmaj.090374"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1177\/0300060519847367"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1610-0387.2006.06053.x"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(15)00527-7"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clindermatol.2016.10.008"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1542\/PEDS.2019-2056L"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.4161\/derm.1.3.9364"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.3892\/etm.2021.9966"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1159\/000246114"},{"issue":"3","key":"e_1_2_10_12_1","first-page":"28","article-title":"Therapeutic and aesthetic uses of photodynamic therapy part two of a five\u2010part series: lasers and light treatments for acne vulgaris promising therapies","volume":"1","author":"Gold MH","year":"2008","journal-title":"J Clin Aesthet Dermatol"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.23099"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1364\/boe.7.002311"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1117\/12.2225434"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.21132"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-020-62715-3"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.5812\/jssc.114161"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10103-022-03645-6"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jadr.2021.100230"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.jid.5700289"}],"container-title":["Journal of Cosmetic Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jocd.15602","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/jocd.15602","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jocd.15602","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,6,6]],"date-time":"2024-06-06T06:08:12Z","timestamp":1717654092000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jocd.15602"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,12,28]]},"references-count":20,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2023,2]]}},"alternative-id":["10.1111\/jocd.15602"],"URL":"https:\/\/doi.org\/10.1111\/jocd.15602","archive":["Portico"],"relation":{},"ISSN":["1473-2130","1473-2165"],"issn-type":[{"value":"1473-2130","type":"print"},{"value":"1473-2165","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,12,28]]},"assertion":[{"value":"2022-10-18","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-12-13","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-12-28","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}