{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,23]],"date-time":"2026-04-23T05:46:05Z","timestamp":1776923165685,"version":"3.51.2"},"reference-count":52,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2023,1,31]],"date-time":"2023-01-31T00:00:00Z","timestamp":1675123200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81971842"],"award-info":[{"award-number":["81971842"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Cosmetic Dermatology"],"published-print":{"date-parts":[[2023,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To evaluate the efficacy of platelet\u2010rich plasma (PRP) in the treatment of androgenetic alopecia, as well as establish an effective treatment protocol and optimal PRP preparation procedure.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We searched the PubMed, Scopus, Embase, Cochrane, CNKI, and Wanfang databases from inception to October 29, 2021, using PROSPERO's International Prospective Register of Systematic Reviews (registration ID: CRD42022295921).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The original literature search revealed 215 reviews; after duplication removal, 89 papers were eliminated, 95 were eliminated after reading the titles and abstracts, and eventually, 28 articles were included after reading the complete text.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>PRP treatment for androgenetic alopecia is effective, and we recommend the following: (1) a PRP volume of at least 0.05\u2009ml\/cm<jats:sup>2<\/jats:sup>, preferably 0.1\u00a0ml\/cm<jats:sup>2<\/jats:sup>; (2) at least three consecutive treatments at an interval of 1\u00a0month; (3) intensive therapy is beneficial and can be provided from 3 to 6\u00a0months after continuous treatment; (4) objective indicators such as hair diameter, hair count; (5) long\u2010term follow\u2010up.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jocd.15617","type":"journal-article","created":{"date-parts":[[2023,1,31]],"date-time":"2023-01-31T10:39:59Z","timestamp":1675161599000},"page":"1463-1476","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["An umbrella review of the use of platelet\u2010rich plasma in the treatment of androgenetic alopecia"],"prefix":"10.1111","volume":"22","author":[{"given":"Caihong","family":"Li","sequence":"first","affiliation":[{"name":"Department of Plastic Surgery China\u2010Japan Union Hospital of Jilin University  Jilin China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lingfeng","family":"Pan","sequence":"additional","affiliation":[{"name":"Department of Plastic Surgery China\u2010Japan Union Hospital of Jilin University  Jilin China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Liehao","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Plastic Surgery China\u2010Japan Union Hospital of Jilin University  Jilin China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiao","family":"Kong","sequence":"additional","affiliation":[{"name":"Department of Plastic Surgery China\u2010Japan Union Hospital of Jilin University  Jilin 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