{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T16:00:42Z","timestamp":1791907242132,"version":"4.3.4"},"reference-count":30,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2023,2,10]],"date-time":"2023-02-10T00:00:00Z","timestamp":1675987200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Cosmetic Dermatology"],"published-print":{"date-parts":[[2023,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Beh\u00e7et's disease is a systemic auto\u2010immune and auto\u2010inflammatory chronic disease in which genetic and environmental factors play a role. Patients with Beh\u00e7et's are at significant risk for developing many comorbidities, including cardiovascular diseases.<\/jats:p><\/jats:sec><jats:sec><jats:title>Aims<\/jats:title><jats:p>It was aimed to investigate the relationship between serum lipid parameters and atherogenic indexes to evaluate the cardiovascular risk status in patients with Beh\u00e7et's disease.<\/jats:p><\/jats:sec><jats:sec><jats:title>Patients\/Methods<\/jats:title><jats:p>This study was designed as a single\u2010center, retrospective case\u2013control study. The study was conducted with 212 patients over 18\u2009years of age, 106 in the case group and 106 in the control group.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>There was a significant difference in lipid values between the patients with Beh\u00e7et's disease and the control group. While the serum triglyceride, total cholesterol, low\u2010density lipoprotein cholesterol (LDL\u2010C), and non\u2010high\u2010density lipoprotein cholesterol (NHC) levels were significantly higher, the high\u2010density lipoprotein cholesterol (HDL\u2010C) level was low in patients with Beh\u00e7et's disease. From atherogenic indexes, Atherogenic Index of Plasma (AIP) (0.03\u2009\u00b1\u20090.27 vs. \u22120.07\u2009\u00b1\u20090.23, <jats:italic>p<\/jats:italic>\u00a0=\u00a00.003), Castelli Risk Index I (CRI\u2010I) (4.24\u2009\u00b1\u20091.07 vs. 3.02\u2009\u00b1\u20090.96, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001), Castelli Risk Index II (CRI\u2010II) (2.65\u2009\u00b1\u20090.81 vs. 1.84\u2009\u00b1\u20090.59, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001) and Atherogenic Coefficient (AC) (3.24\u2009\u00b1\u20091.07 vs. 2.02\u2009\u00b1\u20090.96, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001) levels were significantly higher in patients with Beh\u00e7et's disease.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Our study shows that patients with Beh\u00e7et's have a higher pro\u2010atherogenic lipid profile and atherogenic indexes at high risk. Patients with Beh\u00e7et's have an increased risk of cardiovascular diseases associated with atherosclerosis.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jocd.15647","type":"journal-article","created":{"date-parts":[[2023,2,10]],"date-time":"2023-02-10T08:03:53Z","timestamp":1676016233000},"page":"1887-1892","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Evaluation of pro\u2010atherogenic lipid profile and high atherohenic indexes in patients with Beh\u00e7et's disease: A case\u2013control study"],"prefix":"10.1111","volume":"22","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3561-3192","authenticated-orcid":false,"given":"Onur","family":"Acar","sequence":"first","affiliation":[{"name":"A\u011fr\u0131 Provincial Health Directorate, Republic of Turkey, Ministry of Health  A\u011fr\u0131 Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8480-4561","authenticated-orcid":false,"given":"Gulhan Aksoy","family":"Sarac","sequence":"additional","affiliation":[{"name":"Ufuk University Faculty of Medicine Department of Dermatology  Ankara Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Didem Din\u00e7er","family":"Rota","sequence":"additional","affiliation":[{"name":"Ufuk University Faculty of Medicine Department of Dermatology  Ankara Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hakan","family":"Aksoy","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Memorial Ankara Hospital  Ankara Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,2,10]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clindermatol.2017.06.004"},{"issue":"1","key":"e_1_2_10_3_1","first-page":"65","article-title":"Beh\u00e7et hastal\u0131\u011f\u0131","volume":"1","author":"Aytu\u011far E","year":"2014","journal-title":"Clin Exp Health Sci"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1080\/1744666X.2016.1205486"},{"key":"e_1_2_10_5_1","volume-title":"Behcet Disease","author":"Adil A","year":"2022"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.4103\/jcar.JCar_15_20"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.4103\/0976-9668.280267"},{"issue":"1","key":"e_1_2_10_8_1","first-page":"64","article-title":"AIP\u2014atherogenic index of plasma as a significant predictor of cardiovascular risk: from research to 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