{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,14]],"date-time":"2026-02-14T06:39:46Z","timestamp":1771051186736,"version":"3.50.1"},"reference-count":31,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2023,2,16]],"date-time":"2023-02-16T00:00:00Z","timestamp":1676505600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Cosmetic Dermatology"],"published-print":{"date-parts":[[2023,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Plantar warts are benign, epidermal neoformations, viral, and easily transmitted. Although 30% of these warts disappear spontaneously, the American Association of Dermatology recommends treatment if they cause pain or bleeding.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>The aim of this study was to determine the efficacy of Dermojet\u00ae infiltration using a solution composed of equal parts of 0.9% saline and 2% mepivacaine in the treatment of plantar warts, and to identify the type of necrosis achieved at 7\u201310\u2009days after the infiltration (M1 sample) and at 15\u201317\u2009days (M2 sample).<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>In this analytical prospective observational study, 102 histories were reviewed by the same researcher. The patients were treated with this technique at four private podiatry clinics.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 61.8% of the patients were male. The patients' mean age was 26.6\u2009\u00b1\u200914.10\u2009years. A total percentage of 78.4% of the patients achieved complete elimination of the lesion by the second evaluation and after a single infiltration. Bivariate analysis revealed a significant inverse relationship between treatment efficacy and a history of previous disease (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001) and the period of evolution of the lesion (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001; 95% CI [0.78\u20137.91]). Multivariate linear regression analysis revealed an association with the number of evaluation sessions (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001) and with previous illnesses (<jats:italic>p<\/jats:italic>\u00a0=\u00a00.014). A total percentage of 82.35% presented partial necrosis in the M1 sample and 76.92% had complete necrosis in the M2 sample.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>In 78.4% of the patients considered, the plantar warts treated disappeared after a single infiltration. The variables associated with treatment efficacy were the number of follow\u2010up visits and the existence of associated diseases.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jocd.15680","type":"journal-article","created":{"date-parts":[[2023,2,17]],"date-time":"2023-02-17T06:39:50Z","timestamp":1676615990000},"page":"1980-1987","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Treatment efficacy of 0.9% saline and mepivacaine infiltration with Dermojet\u00ae in eliminating plantar warts"],"prefix":"10.1111","volume":"22","author":[{"given":"Oltra\u2010Romero","family":"Ana\u00a0M","sequence":"first","affiliation":[{"name":"Department of Behavioural Sciences and Health, Nursing Area, Faculty of Medicine University Miguel Hern\u00e1ndez  Sant Joan d'Alacant Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Garcia\u2010L\u00e1zaro","family":"Silvia","sequence":"additional","affiliation":[{"name":"Department of Behavioural Sciences and Health, Nursing Area, Faculty of Medicine University Miguel Hern\u00e1ndez  Sant Joan d'Alacant Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9643-4548","authenticated-orcid":false,"given":"Gracia\u2010S\u00e1nchez","family":"Alba","sequence":"additional","affiliation":[{"name":"Department of Behavioural Sciences and Health, Nursing Area, Faculty of Medicine University Miguel Hern\u00e1ndez  Sant Joan d'Alacant Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Z\u00fanica\u2010Garc\u00eda","family":"Sara","sequence":"additional","affiliation":[{"name":"Department of Behavioural Sciences and Health, Nursing Area, Faculty of Medicine University Miguel Hern\u00e1ndez  Sant Joan d'Alacant Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4766-5723","authenticated-orcid":false,"given":"Chicharro\u2010Luna","family":"Esther","sequence":"additional","affiliation":[{"name":"Department of Behavioural Sciences and Health, Nursing Area, Faculty of Medicine University Miguel Hern\u00e1ndez  Sant Joan d'Alacant Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,2,16]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cpm.2016.02.003"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.7556\/jaoa.2018.024"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2133.2001.04066.x"},{"key":"e_1_2_10_5_1","volume-title":"Dermatolog\u00eda en Medicina General","author":"Fitzpatrick TB","year":"2009"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-5945-6-4"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2012-2946"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2133.1998.02222.x"},{"issue":"2","key":"e_1_2_10_9_1","first-page":"102","article-title":"Human papilloma virus (VPH). 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