{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T20:59:03Z","timestamp":1792616343286,"version":"4.5.0"},"reference-count":26,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2023,5,23]],"date-time":"2023-05-23T00:00:00Z","timestamp":1684800000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Cosmetic Dermatology"],"published-print":{"date-parts":[[2023,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Pediculosis capitis, also known as head lice, is a common problem that affects individuals of different socio\u2010economic backgrounds. Permethrin is generally considered the first\u2010line treatment option for head lice.<\/jats:p><\/jats:sec><jats:sec><jats:title>Aims<\/jats:title><jats:p>The objective of this study was to evaluate and compare the therapeutic effects of three different methods of permethrin treatment for head lice.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>A parallel, randomized clinical trial was conducted on 157 patients with head lice. The participants underwent eye examination and dry combing by a trained professional. The subjects were randomly divided into three groups and treated with one of the three methods of permethrin application: permethrin shampoo for 10\u2009min, permethrin shampoo for 1\u2009h, or permethrin cream for 10\u2009min on a weekly basis for 3\u2009weeks.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of the 157 participants, 154 completed the study. The group treated with permethrin shampoo for 1\u2009h had the shortest average time for eradication of lice at 1.226\u2009\u00b1\u20090.422\u2009weeks, which was significantly lower than the other two groups. Additionally, the 1\u2010h permethrin shampoo group had the lowest time for scalp itching of 2.15\u2009\u00b1\u20090.632\u2009weeks, which was significantly lower than the other two groups. Moreover, the rate of lice eradication in the first week was significantly higher in the 1\u2010h permethrin shampoo group.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The results of this study suggest that the use of 1% permethrin shampoo for 1\u2009h is more effective in eradicating head lice within the first week of treatment and in relieving scalp itching during the second week.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jocd.15817","type":"journal-article","created":{"date-parts":[[2023,5,23]],"date-time":"2023-05-23T09:48:21Z","timestamp":1684835301000},"page":"3065-3071","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Comparing the efficacy of three methods of permethrin application in pediculosis capitis: A randomized clinical trial"],"prefix":"10.1111","volume":"22","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0651-5545","authenticated-orcid":false,"given":"Nasibeh","family":"Ghalandari","sequence":"first","affiliation":[{"name":"Department of Clinical Pharmacy, School of Pharmacy Shahid Beheshti University of Medical Sciences  Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aida","family":"Edalatkhah\u00a0Tatafi","sequence":"additional","affiliation":[{"name":"Department of Clinical Pharmacy, School of Pharmacy Shahid Beheshti University of Medical Sciences  Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5300-349X","authenticated-orcid":false,"given":"Ghader","family":"Mohammadnezhad","sequence":"additional","affiliation":[{"name":"Department of Clinical Pharmacy, School of Pharmacy Shahid Beheshti University of Medical Sciences  Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0571-5940","authenticated-orcid":false,"given":"Maryam","family":"Nasimi","sequence":"additional","affiliation":[{"name":"Tehran University of Medical Sciences  Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6915-6028","authenticated-orcid":false,"given":"Hadi","family":"Esmaily","sequence":"additional","affiliation":[{"name":"Department of Clinical Pharmacy, School of Pharmacy Shahid Beheshti University of Medical Sciences  Tehran Iran"},{"name":"Imam Hossein medical center Shahid Beheshti University of Medical Sciences  Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,5,23]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.apjtb.2016.03.002"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.21101\/cejph.a3750"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.26719\/2012.18.1.43"},{"issue":"4","key":"e_1_2_11_5_1","first-page":"726","article-title":"Pediculosis capitis: treatment options among schoolchildren in Greece","volume":"6","author":"Vladeni S","year":"2012","journal-title":"Health Sci J"},{"issue":"1","key":"e_1_2_11_6_1","first-page":"42","article-title":"Epidemiology of head lice infestation in primary school pupils, in khajeh city, East Azerbaijan province","volume":"4","author":"Shayeghi M","year":"2010","journal-title":"Iran J Arthropod Borne Dis"},{"issue":"1","key":"e_1_2_11_7_1","first-page":"607","article-title":"The prevalence of pediculus capitis among the middle schoolchildren in Fars Province, southern Iran","volume":"4","author":"Davarpanah MA","year":"2013","journal-title":"Caspian J Intern Med"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.318.7180.385"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-4362.2003.01927.x"},{"key":"e_1_2_11_10_1","unstructured":"Control.UCfD. 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