{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,10]],"date-time":"2026-04-10T21:24:15Z","timestamp":1775856255606,"version":"3.50.1"},"reference-count":18,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2023,5,23]],"date-time":"2023-05-23T00:00:00Z","timestamp":1684800000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Cosmetic Dermatology"],"published-print":{"date-parts":[[2023,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To evaluate the clinical efficacy of a combination treatment of traditional Chinese medicine (TCM) in scalp seborrheic dermatitis (SSD) of differing severity.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Our study included patients with typical SSD who visited the Medical Research Center for Hair and Skin at our hospital. Symptoms were evaluated using a \u201c16\u2010point scale\u201d developed at the center. Patients who had mild SSD were treated with Pi Fu Kang Xi Ye (PFKXY), those with moderate SSD were treated with PFKXY combined with Run Zao Zhi Yang Jiao Nang (RZZYJN), and those with severe dermatitis were treated with PFKXY and RZZYJN along with garlicin enteric\u2010coated tablets. Patients were asked to revisit 4\u2009weeks later to evaluate the efficacy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Symptom scores of all patients decreased by (5.48\u2009\u00b1\u20092.51) after treatment as compared with before treatment, and the results of <jats:italic>t<\/jats:italic>\u2010test and correlation test were significant (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.01). The scores of patients with mild, moderate and severe SSD decreased by 3.14\u2009\u00b1\u20091.83, 4.90\u2009\u00b1\u20091.77, and 8.05\u2009\u00b1\u20092.21, respectively, after treatment as compared with before treatment. Among them, the changes in scores of patients with moderate dermatitis before and after treatment were significant in the <jats:italic>t<\/jats:italic>\u2010test and correlation test (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.01).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>In this study, the combination treatment of TCM showed significant efficacy in the treatment of mild, moderate, and severe SSD, and the efficacy was stable, especially for patients with moderate SSD.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jocd.15818","type":"journal-article","created":{"date-parts":[[2023,5,23]],"date-time":"2023-05-23T09:40:31Z","timestamp":1684834831000},"page":"3072-3077","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Clinical efficacy of a combination treatment of traditional Chinese medicine for scalp seborrheic dermatitis"],"prefix":"10.1111","volume":"22","author":[{"given":"Fan","family":"Zhang","sequence":"first","affiliation":[{"name":"Department of Dermatology and Venereology Beijing Jishuitan Hospital Hair Medical Research Center  Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuan\u2010hong","family":"Li","sequence":"additional","affiliation":[{"name":"School of Clinical Medicine Peking University School of Medicine  Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wei","family":"Ren","sequence":"additional","affiliation":[{"name":"School of Clinical Medicine Peking University School of Medicine  Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shu\u2010run","family":"Li","sequence":"additional","affiliation":[{"name":"School of Clinical Medicine Peking University School of Medicine  Beijing 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