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There have been progressive reports of the effects of COVID\u201019 vaccination on cosmetic fillers or prostheses, but they have not been reviewed based on their clinical morphologic patterns. This article reviewed the progress of research on adverse reactions to cosmetic implants after COVID\u201019 vaccination.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We researched the English\u2010language literature up to October 15, 2022, using predefined keywords to identify relevant studies about adverse reactions to cosmetic implants after the COVID\u201019 vaccination, collecting patient characteristics, implant type, the time interval between vaccination and implantation or injection, time of onset, symptoms, treatments, and outcomes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Among the adverse reactions to implants associated with COVID\u201019 vaccination, we distinguished between (1) injectable fillers and (2) surgical prosthetic implants. The most common adverse reactions were at the site of hyaluronic acid injection and breast prosthesis after Pfizer vaccination, mainly DIRs, and mainly manifested as edema, rash, fever, and capsular contracture. This paper also reported the possible causes, treatments of DIRs, and limitations of current studies.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>In this article, we attempted to investigate and discuss all the adverse reactions of cosmetic implants related to COVID\u201019 vaccination in the current literature, to unmask these reactions and make a more accurate assessment of vaccine safety.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jocd.15828","type":"journal-article","created":{"date-parts":[[2023,8,21]],"date-time":"2023-08-21T22:35:04Z","timestamp":1692657304000},"page":"3199-3212","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Adverse reactions to cosmetic implants after <scp>COVID<\/scp>\u201019 vaccination: A literature review"],"prefix":"10.1111","volume":"22","author":[{"given":"Wen\u2010jie","family":"Cheng","sequence":"first","affiliation":[{"name":"Department of Craniomaxillofacial Surgery, Plastic Surgery Hospital, Chinese Academy of Medical Sciences Peking Union Medical College  Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zi\u2010xing","family":"Cai","sequence":"additional","affiliation":[{"name":"Xiamen University Medical College  Fujian China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6625-0841","authenticated-orcid":false,"given":"Xiao\u2010jun","family":"Tang","sequence":"additional","affiliation":[{"name":"Department of Craniomaxillofacial Surgery, Plastic Surgery Hospital, Chinese Academy of Medical Sciences Peking Union Medical College  Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,8,17]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/jocd.14613"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/GOX.0000000000004522"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/jocd.15386"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0041-1740623"},{"key":"e_1_2_11_6_1","unstructured":"The Aesthetic Society.Aesthetic Plastic Surgery National Databank Statistics.2021."},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.3390\/app112210888"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/ajt.16516"},{"issue":"3","key":"e_1_2_11_9_1","first-page":"1663","article-title":"COVID\u201019 vaccines: comparison of biological, pharmacological characteristics and adverse effects of Pfizer\/BioNTech and Moderna vaccines","volume":"25","author":"Meo SA","year":"2021","journal-title":"Eur Rev Med Pharmacol Sci"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1093\/asj\/sjac101"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1186\/s42269-022-00791-3"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00266-021-02554-3"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1093\/asj\/sjab155"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00403-021-02190-6"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1093\/asjof\/ojab021"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.12998\/wjcc.v10.i23.8298"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2021.03.092"},{"issue":"10","key":"e_1_2_11_18_1","first-page":"534","article-title":"Women with silicone breast implants and unexplained systemic symptoms: a descriptive cohort study","volume":"71","author":"Maijers MC","year":"2013","journal-title":"Neth J Med"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2021.11.052"},{"key":"e_1_2_11_20_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00266-014-0367-6"},{"key":"e_1_2_11_21_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjophthalmol-2020-317953"},{"key":"e_1_2_11_22_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0040-1714378"},{"key":"e_1_2_11_23_1","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000028092"},{"key":"e_1_2_11_24_1","doi-asserted-by":"publisher","DOI":"10.3389\/fmed.2022.843793"},{"key":"e_1_2_11_25_1","doi-asserted-by":"publisher","DOI":"10.1111\/jocd.15117"},{"key":"e_1_2_11_26_1","doi-asserted-by":"publisher","DOI":"10.1093\/jbcr\/irab043"},{"key":"e_1_2_11_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.archger.2020.104174"},{"issue":"57","key":"e_1_2_11_28_1","first-page":"236","article-title":"Cardiovascular involvement during COVID\u201019 and clinical implications in elderly patients. 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