{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T03:57:58Z","timestamp":1790740678927,"version":"4.1.0"},"reference-count":53,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2023,8,25]],"date-time":"2023-08-25T00:00:00Z","timestamp":1692921600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Cosmetic Dermatology"],"published-print":{"date-parts":[[2023,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Seborrheic dermatitis is a common chronic inflammatory skin disorder that affects the scalp and is characterized by erythema and oily scales. It could perhaps be difficult to control and could seriously degrade one's quality of life. The study's objective is to assess the effectiveness of intradermal administrations of QR678 Neo\u00ae hair growth factor therapy for the treatment of scalp seborrheic dermatitis in both men and women.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>Forty male and female patients with clinically diagnosed seborrheic dermatitis of the scalp in the age 18\u201345\u2009years, not satisfactorily responding to standard therapy for at least 6\u2009months, were included. 1\u2009mL solution of QR678 Neo\u00ae was administered in the scalp skin of all patients at 3\u2010week interval till eight sessions. Patients were advised to continue with antifungal shampoo and topical antifungal solution with steroid combination which they had been on during the treatment. Assessment of disease severity, dermoscopic evaluation, and self\u2010assessment were done at baseline and at the end of the fourth and the eighth sessions.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Improvement was observed in adherent scalp flaking score after eighth session (mean\u2009=\u200912) compared to baseline (mean\u2009=\u200960). The dermoscopic evaluation showed a noticeable difference from baseline (mean\u2009=\u200911) in erythema and scaling with the Seborrheic Dermatitis Scalp Severity Index tool at the end of treatment (mean\u2009=\u20092). A high satisfaction score was given for the efficiency in the self\u2010assessment questionnaire.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Our study proved that treatment with QR678 Neo\u00ae led to an improvement in the overall scalp condition by the resolution of flaking and inflammation.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jocd.15957","type":"journal-article","created":{"date-parts":[[2023,8,25]],"date-time":"2023-08-25T07:29:14Z","timestamp":1692948554000},"page":"3078-3087","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["A newer approach in the treatment of seborrheic dermatitis with QR678\u00ae and QR678 Neo\u00ae\u2014A prospective pilot study"],"prefix":"10.1111","volume":"22","author":[{"given":"Rinky","family":"Kapoor","sequence":"first","affiliation":[{"name":"Department of Dermatology, Cosmetic Dermatology &amp; Dermato\u2010Surgery &amp; Director The Esthetic 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