{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,16]],"date-time":"2026-06-16T10:56:15Z","timestamp":1781607375082,"version":"3.54.5"},"reference-count":16,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2023,8,29]],"date-time":"2023-08-29T00:00:00Z","timestamp":1693267200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Cosmetic Dermatology"],"published-print":{"date-parts":[[2024,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>UV rays not only cause oxidative damage to the skin, but also damage its barrier function. The use of sunscreen is crucial in preventing skin from UV radiation, but it may have an impact on the function of the skin barrier. While much research has focused on the protective effects of sunscreen against UV oxidative damage, little is known about the impact of daily sunscreen use on the skin barrier.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objective<\/jats:title><jats:p>This study mainly investigated the changes in skin barrier function of volunteers (including those with sensitive skin) before and after using a ceramide\u2010containing sunscreen.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A total of 60 volunteers used SPF30 sunscreen containing ceramide every morning. Using non\u2010invasive methods to detect skin barrier changes in TEWL, hydration, facial redness based on VISIA\u2010CR image, and Erythema index (EI) value after 4\u2009weeks of using ceramide\u2010containing sunscreen. Adverse reactions were also assessed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>After 4\u2009weeks of using ceramide\u2010containing sunscreen, significant reductions were observed in skin redness with both an 11.89% decrease in <jats:italic>a<\/jats:italic>* value and a 5.68% decrease in skin EI, while there was also a significant decrease in transepidermal water loss (TEWL) with a reduction of 22.96%, and a significant increase in skin hydration with a 21.96% increase in the moisture content of the stratum corneum. No adverse events occurred during the entire testing process.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Daily application of ceramide\u2010containing sunscreen can increase skin hydration while enhancing the function of the skin barrier.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jocd.15977","type":"journal-article","created":{"date-parts":[[2023,8,29]],"date-time":"2023-08-29T07:18:17Z","timestamp":1693293497000},"page":"525-528","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Efficacy of ceramide\u2010containing sunscreen on skin barrier"],"prefix":"10.1111","volume":"23","author":[{"given":"Yu","family":"Cao","sequence":"first","affiliation":[{"name":"Dermatology Center Xinhua Hospital, Shanghai Jiaotong University School of Medicine  Shanghai China"},{"name":"Department of Dermatology Xinhua Hospital, Shanghai Jiaotong University School of Medicine  Shanghai China"},{"name":"Institute of Dermatology Shanghai Jiaotong University School of Medicine  Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xianghua","family":"Zhang","sequence":"additional","affiliation":[{"name":"Dermatological Beauty Division L'Or\u00e9al China Co.Ltd  Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaofeng","family":"He","sequence":"additional","affiliation":[{"name":"Research and Innovation Center L'Or\u00e9al China Co.Ltd  Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenna","family":"Wang","sequence":"additional","affiliation":[{"name":"Research and Innovation Center L'Or\u00e9al China Co.Ltd  Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi","family":"Yi","sequence":"additional","affiliation":[{"name":"Research and Innovation Center L'Or\u00e9al China Co.Ltd  Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yunfei","family":"Ai","sequence":"additional","affiliation":[{"name":"Dermatological Beauty Division L'Or\u00e9al China Co.Ltd  Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,8,29]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1467-2494.2004.00241.x"},{"key":"e_1_2_10_3_1","first-page":"52","article-title":"The effects of ultraviolet radiation on skin and skin barrier.","author":"Dan Luo WLXT","year":"2015","journal-title":"2015 National Conference on Integrated Traditional Chinese and Western Medicine 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