{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,20]],"date-time":"2026-07-20T14:17:49Z","timestamp":1784557069532,"version":"3.55.0"},"reference-count":35,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2023,9,7]],"date-time":"2023-09-07T00:00:00Z","timestamp":1694044800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Cosmetic Dermatology"],"published-print":{"date-parts":[[2023,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Alopecia areata (AA) is an autoimmune non\u2010scarring hair loss. The role of micronutrients such as iron, zinc, and vitamins, especially vitamin D, on the natural hair cycle is well defined in literature. This study aims to evaluate the correlation between vitamin D and CRP levels in patients with alopecia areata.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This cross\u2010sectional study was performed from beginning of October 2020 until end of December 2021. Alopecia areata patients over 18\u2009years of age gave their written consent to participate in the study. The severity of the patients' disease was assessed using the Severity of Alopecia Tool. Serum vitamin D and CRP levels were measured and CBC and LFT were also performed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>There were significant differences between the patients with the localized form of AA and its universal form in the following variables: Vitamin D levels, SALT score, WBC, ALKP, and CRP. There was also a significant inverse correlation between CRP and vitamin D levels (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.0001).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Vitamin D deficiency is associated with higher CRP levels, and patients with low serum vitamin D and high CRP levels are at a higher risk of developing the universalis form of AA; therefore, these patients should undergo more aggressive treatments.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jocd.15994","type":"journal-article","created":{"date-parts":[[2023,9,7]],"date-time":"2023-09-07T07:43:51Z","timestamp":1694072631000},"page":"3176-3180","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Inverse correlation between vitamin D and <scp>CRP<\/scp> levels in alopecia areata: A pilot study"],"prefix":"10.1111","volume":"22","author":[{"given":"Fatemeh","family":"Mokhtari","sequence":"first","affiliation":[{"name":"Skin Diseases and Leishmaniasis Research Center, Department of Dermatology Isfahan University of Medical Sciences  Isfahan Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9673-5911","authenticated-orcid":false,"given":"Zakiye","family":"Ganjei","sequence":"additional","affiliation":[{"name":"Department of Dermatology, School of Medicine Alborz University of Medical Sciences  Karaj Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maral","family":"Yazdanpanah","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Faculty of Medicine Shahrekord University of Medical Sciences  Shahrekord Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohsen","family":"Hosseini","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and 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