{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,7]],"date-time":"2026-05-07T06:09:37Z","timestamp":1778134177732,"version":"3.51.4"},"reference-count":47,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2023,10,21]],"date-time":"2023-10-21T00:00:00Z","timestamp":1697846400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2023,10,21]],"date-time":"2023-10-21T00:00:00Z","timestamp":1697846400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"publisher","award":["NRF\u20102021R1F1A1059510"],"award-info":[{"award-number":["NRF\u20102021R1F1A1059510"]}],"id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Cosmetic Dermatology"],"published-print":{"date-parts":[[2024,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>Vitiligo is a disease of acquired depigmentation characterized by the destruction of melanocytes. A theoretical association between low level of 25\u2010hydroxyvitamin D [25(OH)D] and vitiligo has been previously suggested. The objective of this study was to determine the efficacy of intramuscular injection of cholecalciferol with excimer laser compared with the excimer laser alone for vitiligo treatment.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This study included 26 patients diagnosed with non\u2010segmental vitiligo and low serum 25(OH)D levels (&lt;20\u2009ng\/mL). The participants were randomly divided into two groups through randomization. The treatment using a 308\u2010nm excimer laser was administered to both groups, and the study group additionally received cholecalciferol injection.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The Vitiligo Area Scoring Index (VASI) scores showed an 83.6% improvement over the initial score in the study group, whereas the control group showed a 54.7% improvement after 6\u2009months of treatment. After 6\u2009months of treatment, the study group showed a significantly higher proportion of patients who achieved VASI50 and VASI75 compared with the control group.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Intramuscular injection of cholecalciferol can be a supplemental option for the treatment of vitiligo patients with vitamin D deficiency with excimer laser therapy.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jocd.16043","type":"journal-article","created":{"date-parts":[[2023,10,21]],"date-time":"2023-10-21T03:39:46Z","timestamp":1697859586000},"page":"839-848","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Vitamin D supplementation can enhance therapeutic effects of excimer laser in patients with vitiligo"],"prefix":"10.1111","volume":"23","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1523-6951","authenticated-orcid":false,"given":"Jin Cheol","family":"Kim","sequence":"first","affiliation":[{"name":"Department of Dermatology Hallym University Kangnam Sacred Heart Hospital, Hallym University College of Medicine  Seoul Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hye Ran","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Dermatology Hallym University Kangnam Sacred Heart Hospital, Hallym University College of Medicine  Seoul Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jin Seo","family":"Park","sequence":"additional","affiliation":[{"name":"Department of Dermatology Hallym University Kangnam Sacred Heart Hospital, Hallym University College of Medicine  Seoul Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"So Yeon","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Dermatology Hallym University Kangnam Sacred Heart Hospital, Hallym University College of Medicine  Seoul Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hye One","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Dermatology Hallym University Kangnam Sacred Heart Hospital, Hallym University College of Medicine  Seoul Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chun Wook","family":"Park","sequence":"additional","affiliation":[{"name":"Department of Dermatology Hallym University Kangnam Sacred Heart Hospital, Hallym University College of Medicine  Seoul Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bo Young","family":"Chung","sequence":"additional","affiliation":[{"name":"Department of Dermatology Hallym University Kangnam Sacred Heart Hospital, Hallym University College 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