{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,3]],"date-time":"2026-08-03T14:38:45Z","timestamp":1785767925862,"version":"3.56.0"},"reference-count":28,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2023,11,13]],"date-time":"2023-11-13T00:00:00Z","timestamp":1699833600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2023,11,13]],"date-time":"2023-11-13T00:00:00Z","timestamp":1699833600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Cosmetic Dermatology"],"published-print":{"date-parts":[[2024,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Alopecia may decrease patients' quality of life and self\u2010confidence by limiting their social life. Therefore, the main goal of the treatment is to limit or halt the progression of inflammation, scarring, and hair loss. The promising effect of fat injection on hair regrowth, limited adverse effects, and subsiding inflammation can be proof of its efficacy and safety in treating alopecia.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>This review sought to assess the role of autologous fat tissue injection in scarring and non\u2010scarring alopecia.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Accordingly, a thorough search was performed on the Web of Science, Scopus, and PubMed\/Medline databases, as well as the Google Scholar search engine, for studies published from inception until September 1st, 2023, using the related keywords.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Autologous fat grafting (AFG) is a novel and potentially effective modality for treating alopecia, particularly primary and secondary cicatricial alopecia. AFG can be an effective semi\u2010invasive option for treating refractory lichen planopilaris because it induces angiogenesis, which supports hair regrowth. In addition to cicatricial alopecia, AFG held promise for treating non\u2010scarring alopecia, including androgenic alopecia and alopecia areata. The adipose\u2010derived regenerative cells (ADRCs) in adipose tissue (AT) secrete different growth factors, further supporting hair regeneration. Moreover, different anti\u2010inflammatory and anti\u2010oxidative agents are known in AT, preventing further damage to hair follicles.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>AFG can significantly control inflammatory processes, improve signs and symptoms, and increase hair density and diameter.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jocd.16081","type":"journal-article","created":{"date-parts":[[2023,11,13]],"date-time":"2023-11-13T04:58:22Z","timestamp":1699851502000},"page":"758-765","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Autologous adipose tissue injection in the treatment of alopecia: A mini\u2010review"],"prefix":"10.1111","volume":"23","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1657-1487","authenticated-orcid":false,"given":"Sara","family":"Sadeghi","sequence":"first","affiliation":[{"name":"Rasool Akram Medical Complex Clinical Research Development Center (RCRDC) Iran University of Medical Sciences  Tehran Iran"},{"name":"Department of Medicine, New York Health System South Brooklyn Hospital  New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7309-4066","authenticated-orcid":false,"given":"Yekta","family":"Ghane","sequence":"additional","affiliation":[{"name":"School of Medicine Tehran University of Medical Sciences  Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6323-9252","authenticated-orcid":false,"given":"Nima","family":"Hajizadeh","sequence":"additional","affiliation":[{"name":"Rasool Akram Medical Complex Clinical Research 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