{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T18:40:53Z","timestamp":1789497653843,"version":"build-2803163510"},"reference-count":25,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2023,12,4]],"date-time":"2023-12-04T00:00:00Z","timestamp":1701648000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2023,12,4]],"date-time":"2023-12-04T00:00:00Z","timestamp":1701648000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Cosmetic Dermatology"],"published-print":{"date-parts":[[2024,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Hair serum is recommended therapy for the management of hair fall problems. People of all ages suffer from hair fall.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>To evaluate safety and efficacy of hair growth promoting product in healthy adult subjects with hair fall complaints (Alopecia).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>In this safety and efficacy clinical study, 32 healthy individuals (aged 18\u201345 years) experiencing hair loss were enrolled. Participants applied 0.5\u2009mL of the product to the affected scalp area daily for 60\u2009days. The study evaluated various factors, including hair growth rate, thickness, density, scalp condition using CASLite\u2010Nova, anagen\u2010to\u2010telogen ratio, hair fall reduction, overall hair and scalp appearance, hair strength, and participants' subjective perceptions of the product.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Highly statistically significant improvement was observed in hair growth rate, thickness, and density at Day 30 and Day 60. Hair growth rate increased (\n                      <jats:italic>p<\/jats:italic>\n                      \u2010value &lt;0.01) by 10.52% in 30\u2009days and 31.62% in 60\u2009days after test product application. Average hair growth increased by 424.21\u2009\u03bcm\/day and 487.31\u2009\u03bcm\/day at Day 30 and 60 respectively. The hair growth improved by up to 1.5 times after 60\u2009days of usage in healthy subjects with hair fall complaints. No adverse events or product\u2010related adverse events were reported.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Hair serum containing REGENDIL\u2122 (Redensyl, AnaGain, Procapil, Capilia longa), and 5\u2009kDa hyaluronic acid was efficacious and well tolerable in reducing hair fall (Alopecia). Hair serum significantly improved hair growth, hair density, hair thickness, and hair strength within 60\u2009days of usage, thereby demonstrating it worth as a beneficial inclusion as a daily haircare product.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jocd.16084","type":"journal-article","created":{"date-parts":[[2023,12,5]],"date-time":"2023-12-05T02:10:36Z","timestamp":1701742236000},"page":"938-948","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Safety and efficacy of REGENDIL\u2122 infused hair growth promoting product in adult human subject having hair fall complaints (alopecia)"],"prefix":"10.1111","volume":"23","author":[{"given":"Apeksha","family":"Merja","sequence":"first","affiliation":[{"name":"NovoBliss Research Private Limited  Ahmedabad India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nayan","family":"Patel","sequence":"additional","affiliation":[{"name":"NovoBliss Research Private Limited  Ahmedabad India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maheshvari","family":"Patel","sequence":"additional","affiliation":[{"name":"NovoBliss Research Private Limited  Ahmedabad India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saurav","family":"Patnaik","sequence":"additional","affiliation":[{"name":"Anveya Living Private Limited  Gurugram India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Asrar","family":"Ahmed","sequence":"additional","affiliation":[{"name":"Anveya Living Private Limited  Gurugram India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shatakshi","family":"Maulekhi","sequence":"additional","affiliation":[{"name":"Anveya Living Private Limited  Gurugram India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,12,4]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.3949\/ccjm.76a.0808019487557"},{"issue":"5","key":"e_1_2_12_3_1","first-page":"1007","article-title":"Alopecia in women","volume":"67","author":"Thiedke CC","year":"2003","journal-title":"Am Fam Physician"},{"key":"e_1_2_12_4_1","volume-title":"Androgenetic Alopecia","author":"Ho CH","year":"2022"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.317.7162.8659748188"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1991.tb03277.x1993141"},{"key":"e_1_2_12_7_1","first-page":"1","volume-title":"The Physiology and Embryology of Hair Growth. 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