{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,27]],"date-time":"2026-07-27T11:56:03Z","timestamp":1785153363622,"version":"3.55.0"},"reference-count":37,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2023,12,18]],"date-time":"2023-12-18T00:00:00Z","timestamp":1702857600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Cosmetic Dermatology"],"published-print":{"date-parts":[[2024,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Vitiligo is a kind of refractory, autoimmune locally, or systemically generalized depigmentation spots caused by the disappearance of melanocyte function in the skin. Acupuncture and related therapies are extensively utilized for treating vitiligo in China. The objective of this study is to succinctly encapsulate and meticulously assess the methodological and reporting caliber of systematic reviews (SRs) pertaining to acupuncture and associated therapeutic approaches, while concurrently offering an all\u2010encompassing body of evidence elucidating their efficacy and safety in the treatment of vitiligo.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We performed an electronic literature search in eight databases to identify SRs that evaluated the efficacy of acupuncture therapy for vitiligo. The Assessment of Multiple Systematic Reviews 2 (AMSTAR 2) tool was used to evaluate the methodological and reporting quality of these SRs. The preferred reporting items for SRs and meta\u2010analyses were followed according to PRISMA (2020) guidelines. Additionally, the risk of bias in systematic reviews (ROBIS) was assessed to evaluate potential bias. The quality of evidence for outcome measures was evaluated using the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) framework.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>This study included 10 SRs and assessed a total of 13 outcome measures, all of which were published before June 2023. Acupuncture therapy was more effective than control conditions for the treatment of Vitiligo. The AMSTAR\u20102 results indicated a critical deficiency in the methodological quality of all SRs, with items 7 and 16 demonstrating notably low quality. The reporting quality of the included SRs according to PRISMA was deemed unsatisfactory, with significant reporting flaws identified in the areas of Protocol and registration, Risk of bias across studies, Study selection, and Limitations. According to the ROBIS assessment, 5 out of the total number of SRs (50.00%) were found to have a high risk of bias. Out of the total of 62 outcomes evaluated using the GRADE framework, 9 outcomes (14.51%) exhibited high\u2010quality evidence, 20 outcomes (32.26%) demonstrated moderate\u2010quality evidence, 19 outcomes (30.65%) presented low\u2010quality evidence, while 14 outcomes (22.58%) indicated very low\u2010quality evidence.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>This overview shows that Acupuncture therapy was more effective than the control treatment for Vitiligo. Nevertheless, given the subpar methodological quality of the reviews, we recommend conducting studies with stricter designs, larger sample sizes, and improved methodological and reporting quality to yield more robust evidence.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jocd.16107","type":"journal-article","created":{"date-parts":[[2023,12,18]],"date-time":"2023-12-18T08:10:01Z","timestamp":1702887001000},"page":"1187-1204","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Acupuncture for vitiligo: An overview of systematic reviews and meta\u2010analysis"],"prefix":"10.1111","volume":"23","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9607-4386","authenticated-orcid":false,"given":"Jisen","family":"Zhao","sequence":"first","affiliation":[{"name":"Shandong University of Traditional Chinese Medicine  Ji'nan City Shandong China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-1705-9328","authenticated-orcid":false,"given":"Xueqing","family":"Gong","sequence":"additional","affiliation":[{"name":"Shandong University of Traditional Chinese Medicine  Ji'nan City Shandong China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9697-8748","authenticated-orcid":false,"given":"RuiRui","family":"Hou","sequence":"additional","affiliation":[{"name":"Shandong University of Traditional Chinese Medicine  Ji'nan City Shandong China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-6918-1712","authenticated-orcid":false,"given":"Dong","family":"Guo","sequence":"additional","affiliation":[{"name":"Shandong University of Traditional Chinese Medicine  Ji'nan City Shandong China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,12,18]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2010.11.061"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1159\/000506103"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-3083.2007.02228"},{"issue":"05","key":"e_1_2_8_5_1","first-page":"309","article-title":"Update of health\u2010related quality\u2010of\u2010life scales applied in patients with vitiligo","volume":"35","author":"Zhao H","year":"2019","journal-title":"China J Lepr Skin Dis"},{"key":"e_1_2_8_6_1","first-page":"387","article-title":"Research progress of the pathogenesis of melanocyte and vitiligo","volume":"17","author":"Zhou HY","year":"2019","journal-title":"J Diag Ther Dermato Venereol"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.autrev.2011.02.004"},{"key":"e_1_2_8_8_1","first-page":"142","article-title":"Advances in the drug treatment of vitiligo","volume":"39","author":"Yang YW","year":"2018","journal-title":"World Clin Drugs"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD003263.pub3"},{"key":"e_1_2_8_10_1","first-page":"4163","article-title":"Research progress of acupuncture and moxibustion treatment of vitiligo","volume":"36","author":"Zhao XQ","year":"2021","journal-title":"China J Tradit Chin Med Pharm"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.13193\/j.issn.1673-7717.2017.12.042"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jclinepi.2008.10.009"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jclinepi.2014.12.009"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.j4008"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13643-021-01626-4"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.n160"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jclinepi.2015.06.005"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.a139"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1177\/0013164491511008"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.16808\/j.cnki.issn1003-7705.2016.04.087"},{"key":"e_1_2_8_21_1","first-page":"1172","article-title":"A meta\u2010analysis on randomized controlled trial of fire needle combined with phototherapy for vitiligo","volume":"48","author":"Wang YY","year":"2019","journal-title":"Chongqing Med"},{"key":"e_1_2_8_22_1","first-page":"2545","article-title":"Meta analysis of efficacy and safety of fire acupuncture in the treatment of vitiligo","volume":"31","author":"Yang XY","year":"2020","journal-title":"Lishizhen Med Mater Medica Res"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1155\/2020\/8492097"},{"key":"e_1_2_8_24_1","first-page":"84","article-title":"Meta analysis of fire needle combined with 308\u2009nm excimer laser therapy for vitiligo","volume":"42","author":"Liu JY","year":"2021","journal-title":"J Navy Med"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.19917\/j.cnki.1005-0779.021100"},{"key":"e_1_2_8_26_1","first-page":"74","article-title":"Meta analysis of fire needle combined with external medication in the treatment of vitiligo","volume":"30","author":"Wang F","year":"2021","journal-title":"Chin J Ethnomed Ethnopharm"},{"key":"e_1_2_8_27_1","doi-asserted-by":"publisher","DOI":"10.15909\/j.cnki.cn61-1347\/r.004741"},{"key":"e_1_2_8_28_1","first-page":"276","article-title":"Meta\u2010analysis of the efficacy and safety of the combination of millifire needle and tacrolimus ointment in the treatment of vitiligo","volume":"41","author":"Liu LY","year":"2021","journal-title":"Int J Tradit Chin Med"},{"key":"e_1_2_8_29_1","doi-asserted-by":"publisher","DOI":"10.1155\/2023\/6984149"},{"key":"e_1_2_8_30_1","doi-asserted-by":"publisher","DOI":"10.1089\/acm.2019.0409"},{"key":"e_1_2_8_31_1","doi-asserted-by":"publisher","DOI":"10.13457\/j.cnki.jncm.2014.08.077"},{"key":"e_1_2_8_32_1","doi-asserted-by":"publisher","DOI":"10.13192\/j.issn.1000-1719.2017.07.050"},{"key":"e_1_2_8_33_1","first-page":"45","article-title":"Clinical study on the treatment of chronic eczema with spleen deficiency and dampness accumulation syndrome by combination of filiform needle and fire needle dense needling","volume":"28","author":"Li XL","year":"2023","journal-title":"Guid J Tradit Chin Med Pharm"},{"key":"e_1_2_8_34_1","first-page":"1132","article-title":"Clinical observation on 45 patients with vitiligo treated by 308\u2009nm excimer laser combined fractional carbon dioxide laser","volume":"30","author":"Zhang DY","year":"2016","journal-title":"Chin J Derm Venereol"},{"key":"e_1_2_8_35_1","first-page":"114","article-title":"The effect of heat treatment on the activity of normal human melanocytes cultured in\u00a0vitro","volume":"02","author":"Niu JR","year":"2011","journal-title":"Chin J Dermatol"},{"key":"e_1_2_8_36_1","first-page":"233","article-title":"The effect of heat treatment on the function of melanocytes in guinea pig skin","volume":"27","author":"Yan WT","year":"2013","journal-title":"Chin J Derm Venereol"},{"key":"e_1_2_8_37_1","doi-asserted-by":"publisher","DOI":"10.1155\/2022\/2094589"},{"key":"e_1_2_8_38_1","doi-asserted-by":"publisher","DOI":"10.19917\/j.cnki.1005-0779.021100"}],"container-title":["Journal of Cosmetic Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jocd.16107","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,3,28]],"date-time":"2024-03-28T03:15:28Z","timestamp":1711595728000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jocd.16107"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,12,18]]},"references-count":37,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2024,4]]}},"alternative-id":["10.1111\/jocd.16107"],"URL":"https:\/\/doi.org\/10.1111\/jocd.16107","archive":["Portico"],"relation":{},"ISSN":["1473-2130","1473-2165"],"issn-type":[{"value":"1473-2130","type":"print"},{"value":"1473-2165","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,12,18]]},"assertion":[{"value":"2023-10-03","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-11-07","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-12-18","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}