{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T11:39:26Z","timestamp":1792237166581,"version":"4.4.0"},"reference-count":38,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2023,11,29]],"date-time":"2023-11-29T00:00:00Z","timestamp":1701216000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100013129","name":"Ministry of SMEs and Startups","doi-asserted-by":"publisher","award":["S3193207"],"award-info":[{"award-number":["S3193207"]}],"id":[{"id":"10.13039\/501100013129","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Cosmetic Dermatology"],"published-print":{"date-parts":[[2024,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>\n                      <jats:italic>Sargassum horneri<\/jats:italic>\n                      came ashore after flowing from the South China Sea to Jeju Island a few years ago. This caused a significant environmental impact on coastal areas where\n                      <jats:italic>S. horneri<\/jats:italic>\n                      has accumulated because of decomposition and the release of toxic substances, such as hydrogen sulfide.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>\n                      In this study, we evaluated a biological ingredient prepared from fucoidan\u2010rich\n                      <jats:italic>S. horneri<\/jats:italic>\n                      and demonstrated its antiwrinkle effects on ultraviolet B (UVB)\u2010induced fibroblast cells.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods<\/jats:title>\n                    <jats:p>\n                      Fucoidan samples from\n                      <jats:italic>S. horneri<\/jats:italic>\n                      were prepared according to a previously published process with modifications. The compositional analysis of\n                      <jats:italic>S. horneri<\/jats:italic>\n                      fucoidan extract (SHFE) as well as its effects on antiaging were examined to determine its utility as a functional material.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>SHFE exhibited antioxidant properties using 1,1\u2010diphenyl\u20102\u2010picrylhydrazyl (DPPH) radical scavenging assay. Treatment of UVB\u2010induced fibroblasts with SHFE significantly increased the synthesis of procollagen compared with adenosine treatment and inhibited MMP\u20101 and MMP\u20103 expression. In a clinical study, SHFE lotion improved skin barrier effects in forearms and transepidermal water loss (TEWL) values were reduced after 3\u2009weeks of use compared with a placebo.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>SHFE has utility as an additive with functional antiaging effects for a range of cosmetic products as it restores skin hydration in the epidermal barrier.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jocd.16108","type":"journal-article","created":{"date-parts":[[2023,11,30]],"date-time":"2023-11-30T02:19:25Z","timestamp":1701310765000},"page":"1365-1373","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":28,"title":["The effects of fucoidan\u2010rich polysaccharides extracted from\n                    <i>Sargassum horneri<\/i>\n                    on enhancing collagen\u2010related skin barrier function as a potential cosmetic product"],"prefix":"10.1111","volume":"23","author":[{"given":"Jung\u2010Wook","family":"Kang","sequence":"first","affiliation":[{"name":"College of Pharmacy Research Institute of Pharmaceutical Sciences, Kyungpook National University  Daegu Republic of Korea"},{"name":"College of Fusion and Convergence Seowon University  Cheongju Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seung Hun","family":"Hyun","sequence":"additional","affiliation":[{"name":"Durae Corporation Jeju Bio Center  Jeju\u2010si Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hyo\u2010Min","family":"Kim","sequence":"additional","affiliation":[{"name":"College of Pharmacy Research Institute of Pharmaceutical Sciences, Kyungpook National University  Daegu Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sook\u2010Young","family":"Park","sequence":"additional","affiliation":[{"name":"Human Interface Media Center Jeju National University  Jeju\u2010si Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jung\u2010A","family":"Lee","sequence":"additional","affiliation":[{"name":"Human Interface Media Center Jeju National University  Jeju\u2010si Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"In\u2010Chul","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of cosmetic science and technology Seowon University  Cheongju Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jong\u2010Sup","family":"Bae","sequence":"additional","affiliation":[{"name":"College of Pharmacy Research Institute of Pharmaceutical Sciences, Kyungpook National University  Daegu Republic of 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