{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T22:17:23Z","timestamp":1777933043732,"version":"3.51.4"},"reference-count":29,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2024,1,26]],"date-time":"2024-01-26T00:00:00Z","timestamp":1706227200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2024,1,26]],"date-time":"2024-01-26T00:00:00Z","timestamp":1706227200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Cosmetic Dermatology"],"published-print":{"date-parts":[[2024,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Jawoongo is used to treat and prevent skin issues such as dry and keratinization disorders, burns, trauma, pigmentation, scarring, and inflammatory skin conditions. In this study, the efficacy and safety of 0.47% Jawoongo extract\u2010containing soap (JAUN\u2010CS) were assessed in terms of skin improvement effects such as cleansing, moisturizing, sebum secretion management, and skin elasticity enhancement.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Twenty healthy adult men and women aged 20\u201360\u2009years old took part in the study. Before and after using JAUN\u2010CS, the participants were divided into groups, and various skin improvement effects were measured utilizing machines such as the Corneometer, Tewameter TM 300, and Visioscan. A dermatologist analyzed the product's safety in accordance with Frosch &amp; Kligman and the Cosmetic, Toiletry, and Fragrance Association (CTFA) rules.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Using JAUN reduced the amount of base and point makeup by 25.7% and 76.7%, respectively. Also, JAUN showed a great facial exfoliation effect by removing the old and lifted skin keratins by 84.7% and 20.3%, respectively. Impurities in facial pores decreased by 58%, too. Furthermore, JAUN increased the moisture content of deep skin and skin surface by 3.5% and 74.0%, and skin elasticity by 2.8%. Skin tone, skin texture, skin radiance, and skin barrier all showed improvements of 3.3%, 20.0%, 15.0%, and 115.2%, respectively. Lastly, cleansing with JAUN successfully enhanced the condition of the youth triangle by 7.6%, while TEWL significantly decreased by 52.7%. Neither the JAUN nor the control group soap showed any adverse reactions, such as erythema or allergies, during the testing period.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The results of this study demonstrated that JAUN is safe for human use and has various skin\u2010improving properties, making Jawoongo a promising natural material for the development of functional cosmetics in the future.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jocd.16199","type":"journal-article","created":{"date-parts":[[2024,1,26]],"date-time":"2024-01-26T04:35:25Z","timestamp":1706243725000},"page":"1862-1874","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["The effects of Jawoongo soap on skin improvement"],"prefix":"10.1111","volume":"23","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7818-0529","authenticated-orcid":false,"given":"Sarang","family":"Oh","sequence":"first","affiliation":[{"name":"College of Life Science Kyung Hee University  Yongin\u2010si Gyeong\u2010gi\u2010do Korea"},{"name":"Snowwhitefactory Co., Ltd.  Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hongyong","family":"Kim","sequence":"additional","affiliation":[{"name":"College of Life Science Kyung Hee University  Yongin\u2010si Gyeong\u2010gi\u2010do Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Myeongju","family":"Kim","sequence":"additional","affiliation":[{"name":"College of Life Science Kyung Hee University  Yongin\u2010si Gyeong\u2010gi\u2010do Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiangji","family":"Jin","sequence":"additional","affiliation":[{"name":"Department of Pharmacology, School of Medicine Kyung Hee University  Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3398-4627","authenticated-orcid":false,"given":"Shengdao","family":"Zheng","sequence":"additional","affiliation":[{"name":"College of Life Science Kyung Hee University  Yongin\u2010si Gyeong\u2010gi\u2010do Korea"},{"name":"Snowwhitefactory Co., Ltd.  Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9369-6542","authenticated-orcid":false,"given":"Tae\u2010Hoo","family":"Yi","sequence":"additional","affiliation":[{"name":"College of Life Science Kyung Hee University  Yongin\u2010si Gyeong\u2010gi\u2010do Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,1,26]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0190-9622(89)70227-9"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms140612222"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.abo0693"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1396-0296.2004.04s1005.x"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1523-1747.2003.12359.x"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms232113071"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/GOX.0000000000001152"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.1128\/aem.48.2.338-341.1984"},{"issue":"3","key":"e_1_2_12_10_1","first-page":"229","article-title":"Why is sodium cocoyl isethionate (SCI) mild to the skin barrier? \u2013 An in\u00a0vitro investigation based on the relative sizes of the SCI micelles and the skin aqueous pores","volume":"58","author":"Ghosh S","year":"2007","journal-title":"J Cosmet Sci"},{"key":"e_1_2_12_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jep.2016.10.031"},{"key":"e_1_2_12_12_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12906-018-2280-z"},{"key":"e_1_2_12_13_1","doi-asserted-by":"publisher","DOI":"10.1080\/14786419.2018.1431632"},{"key":"e_1_2_12_14_1","doi-asserted-by":"publisher","DOI":"10.3390\/app131810425"},{"key":"e_1_2_12_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cbi.2014.10.021"},{"key":"e_1_2_12_16_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms231810403"},{"key":"e_1_2_12_17_1","doi-asserted-by":"publisher","DOI":"10.3390\/nu13093209"},{"key":"e_1_2_12_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jep.2020.113039"},{"key":"e_1_2_12_19_1","doi-asserted-by":"publisher","DOI":"10.3390\/nu7064862"},{"key":"e_1_2_12_20_1","doi-asserted-by":"publisher","DOI":"10.1155\/2018\/2450712"},{"key":"e_1_2_12_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jep.2012.07.019"},{"key":"e_1_2_12_22_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00403-021-02197-z"},{"key":"e_1_2_12_23_1","doi-asserted-by":"publisher","DOI":"10.1254\/jjp.88.285"},{"key":"e_1_2_12_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1346-8138.2004.tb00565.x"},{"key":"e_1_2_12_25_1","doi-asserted-by":"publisher","DOI":"10.1002\/mabi.202300220"},{"key":"e_1_2_12_26_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms16047753"},{"key":"e_1_2_12_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.otsr.2016.01.020"},{"key":"e_1_2_12_28_1","doi-asserted-by":"publisher","DOI":"10.3390\/microorganisms9102132"},{"key":"e_1_2_12_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0300-483x(03)00150-1"},{"key":"e_1_2_12_30_1","doi-asserted-by":"publisher","DOI":"10.1172\/jci.insight.145185"}],"container-title":["Journal of Cosmetic Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jocd.16199","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/jocd.16199","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jocd.16199","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T01:37:29Z","timestamp":1777685849000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jocd.16199"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,1,26]]},"references-count":29,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2024,5]]}},"alternative-id":["10.1111\/jocd.16199"],"URL":"https:\/\/doi.org\/10.1111\/jocd.16199","archive":["Portico"],"relation":{},"ISSN":["1473-2130","1473-2165"],"issn-type":[{"value":"1473-2130","type":"print"},{"value":"1473-2165","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,1,26]]},"assertion":[{"value":"2023-10-23","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-01-16","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-01-26","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}