{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T22:17:11Z","timestamp":1777933031833,"version":"3.51.4"},"reference-count":27,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2024,2,4]],"date-time":"2024-02-04T00:00:00Z","timestamp":1707004800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2024,2,4]],"date-time":"2024-02-04T00:00:00Z","timestamp":1707004800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Cosmetic Dermatology"],"published-print":{"date-parts":[[2024,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Hand eczema (HE) is a common and heterogeneous condition. It has a wide range of etiologies and clinical manifestations. In this study the efficacy of triamcinolone 0.1% cream and sulfur 2% creams was compared in treating patients with HE.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This randomized, triple\u2010blind clinical trial was performed on 70 patients with HE (including 70 right and 70 left hands). In this study, two creams were used including triamcinolone 0.1% and sulfur 2.0%. Patients were treated with these creams twice a day (once in every 12\u2009h) for 4\u2009weeks. Follow\u2010up was 4\u2009weeks after treatment. Hand Eczema Severity Index (HECSI), itching, dryness, burning sensation, and erythema scores were collected three times during the study and compared between treatment regimens.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Findings showed that both triamcinolone (0.1%) and sulfur (2.0%) creams could significantly reduce the scores of HECSI, itching, dryness, burning sensation, and erythema, and the therapeutic effects lasted for at least 4\u2009weeks after cessation of topical treatment.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Topical sulfur cream (2.0%) is as effective as triamcinolone (0.1%) cream in treatment of HE without any prominent adverse reactions.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jocd.16208","type":"journal-article","created":{"date-parts":[[2024,2,5]],"date-time":"2024-02-05T00:44:11Z","timestamp":1707093851000},"page":"1753-1757","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Comparison of the effect of topical triamcinolone 0.1% cream with sulfur 2.0% cream in the treatment of patients with hand eczema: A randomized controlled trial"],"prefix":"10.1111","volume":"23","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4377-4378","authenticated-orcid":false,"given":"Ali","family":"Asilian","sequence":"first","affiliation":[{"name":"Department of Dermatology, School of Medicine Isfahan University of Medical Sciences  Isfahan Iran"},{"name":"Department of Dermatology, Skin and Leishmaniasis Research Center Isfahan University of Medical Sciences  Isfahan Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3089-5437","authenticated-orcid":false,"given":"Parisa","family":"Mohammadian","sequence":"additional","affiliation":[{"name":"Department of Dermatology, School of Medicine Isfahan University of Medical Sciences  Isfahan Iran"},{"name":"Department of Dermatology, Skin and Leishmaniasis Research Center Isfahan University of Medical Sciences  Isfahan Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seyed Mohsen","family":"Hosseini","sequence":"additional","affiliation":[{"name":"Department of Biostatistics &amp; Epidemiology School of Public Health, Isfahan University of Medical Sciences  Isfahan Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Farzad","family":"Heidaripour","sequence":"additional","affiliation":[{"name":"Sina Daru International, Suba Laboratory  Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amir","family":"Yekta","sequence":"additional","affiliation":[{"name":"Sina Daru International, Suba Laboratory  Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5754-0516","authenticated-orcid":false,"given":"Mohammad Reza","family":"Nateghi","sequence":"additional","affiliation":[{"name":"Sarem Academy of Sciences, Sarem Hospital  Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,2,4]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.2008.01362.x"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.2147\/TCRM.S292504"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.16062"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0536.2001.044003166.x"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.2007.01179.x"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.1984.tb00018.x"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.18911"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2004.06305.x"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40271-019-00373-y"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/dth.12840"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.13057"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.2340\/0001555576371376"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1177\/1203475416670364"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12887-016-0607-9"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(88)70079-1"},{"key":"e_1_2_10_17_1","unstructured":"OkouchiS.Effects of sulfur hot spring water with reductive characteristic on the skin. The Proceedings of the 62nd General Assembly and International Thermalism\/Scientific Congress of the world Federation of hydrotherapy and Climatotherapy at Yokohama Japan 20092009."},{"key":"e_1_2_10_18_1","first-page":"427","article-title":"The use of sulfur in dermatology","volume":"3","author":"Gupta AK","year":"2004","journal-title":"J Drugs Dermatol"},{"key":"e_1_2_10_19_1","first-page":"234","article-title":"The multifunctionality of 10% sodium sulfacetamide, 5% sulfur emollient foam in the treatment of inflammatory facial dermatoses","volume":"9","author":"Draelos ZD","year":"2010","journal-title":"J Drugs Dermatol"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.3934\/microbiol.2021029"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525-1470.1991.tb00844.x"},{"key":"e_1_2_10_22_1","first-page":"28","article-title":"Benzoyl peroxide and sulfur: foundation for acne management","volume":"95","author":"Wilkinson R","year":"1966","journal-title":"Can Med Assoc J"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.jid.5700781"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2009.09099.x"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.1080\/13543784.2022.2087059"},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.2340\/0001555564358359"},{"key":"e_1_2_10_27_1","doi-asserted-by":"publisher","DOI":"10.1089\/jmf.2012.2275"},{"key":"e_1_2_10_28_1","volume-title":"Drugs and Lactation Database (LactMed\u00ae)","author":"Bethesda M","year":"2006"}],"container-title":["Journal of Cosmetic Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jocd.16208","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/jocd.16208","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jocd.16208","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T01:37:12Z","timestamp":1777685832000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jocd.16208"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,2,4]]},"references-count":27,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2024,5]]}},"alternative-id":["10.1111\/jocd.16208"],"URL":"https:\/\/doi.org\/10.1111\/jocd.16208","archive":["Portico"],"relation":{},"ISSN":["1473-2130","1473-2165"],"issn-type":[{"value":"1473-2130","type":"print"},{"value":"1473-2165","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,2,4]]},"assertion":[{"value":"2023-12-11","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-01-22","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-02-04","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}