{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T01:58:51Z","timestamp":1785549531207,"version":"3.56.0"},"reference-count":17,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2024,2,17]],"date-time":"2024-02-17T00:00:00Z","timestamp":1708128000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Cosmetic Dermatology"],"published-print":{"date-parts":[[2024,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>The protection for different skin types with impaired skin barrier in the market is insufficient.<\/jats:p><\/jats:sec><jats:sec><jats:title>Aim<\/jats:title><jats:p>To evaluate the efficacy and safety of a panthenol\u2010enriched mask (La Roche\u2010Posay Mask Pro) in addressing various skin barrier impairment subgroups, including dry sensitive, oily sensitive, and oily acne skin.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A total of 177 participants were enrolled in the study and divided into three subgroups based on their skin type. Participants used the mask following the specified protocol, with measurements taken for skin hydration, transepidermal water loss (TEWL), sebum content, and skin redness\u2014factors that are directly influenced by skin barrier function. Assessments were conducted at baseline and after 1\u2009day (tested 15\u2009min post\u2010application), 7\u2009days, and 14\u2009days of application using Sebumeter, Tewameter, Corneometer, Mexameter, and VISIA.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Results showed significant improvements in skin parameters across all subgroups. In the dry sensitive skin subgroup, the mask increased skin hydration, sebum content, and reduced redness. For the oily sensitive skin subgroup, the mask regulated sebum production and improved skin hydration. In the oily acne skin subgroup, the mask reduced sebum content, redness, TEWL, and post\u2010inflammatory erythema and hyperpigmentation. Tolerance was excellent for all skin types, with no adverse reactions observed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>This study highlights the efficacy and safety of the panthenol\u2010enriched LRP Mask Pro for individuals with distinct skin barrier impairment subgroups. The mask's versatile formulation and proven efficacy make it a valuable skincare product for addressing various skin concerns and achieving healthier, more balanced skin.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jocd.16231","type":"journal-article","created":{"date-parts":[[2024,2,17]],"date-time":"2024-02-17T08:03:56Z","timestamp":1708157036000},"page":"2109-2116","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Efficacy and safety of a panthenol\u2010enriched mask for individuals with distinct impaired skin barrier subtypes"],"prefix":"10.1111","volume":"23","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1690-7224","authenticated-orcid":false,"given":"Xianghua","family":"Zhang","sequence":"first","affiliation":[{"name":"L'Oreal China  Shanghai 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