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An alternative approach to treating acne could involve using a cosmetic facial mask containing herbal ingredients such as Curcumin and<jats:italic>Rosa Damascena<\/jats:italic>extract for its antibacterial properties.<\/jats:p><\/jats:sec><jats:sec><jats:title>Aims<\/jats:title><jats:p>This study aims to create and try out a peel\u2010off mask gel made from Curcumin and<jats:italic>R. Damascena<\/jats:italic>extract. This gel is intended to have the ability to kill bacteria such as<jats:italic>Staphylococcus aureus<\/jats:italic>,<jats:italic>Escherichia coli<\/jats:italic>, and<jats:italic>Propionibacterium acnes<\/jats:italic>and remove dead cells from the skin surface.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The peel\u2010off mask was made using polyvinyl alcohol (PVA) in 8% and 10% as solidifier. The evaluation of peel\u2010off masks comprises the examination of physiochemical and mechanical aspects. Furthermore, their longevity, effectiveness, and antibacterial properties are also considered.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The white color, pleasant smell, and soft texture were the defining features of the peel\u2010off gel mask. The changes in PVA affect the pH level, thickness, and how quickly the peel\u2010off mask dries. The stability test found that the peel\u2010off mask had no significant physical changes when exposed to freezing and thawing. However, there were some differences in color and separation when using the real\u2010time method. A prepared peel\u2010off mask containing 10% PVA and curcumin works best against<jats:italic>P. acne<\/jats:italic>. The amount of PVA in the formula affected the physical and chemical qualities, but it did not impact on the antibacterial abilities of the peel\u2010off mask gel. The best formula that gives the best results uses 10% PVA\u2009+\u2009curcumin.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Using the Curcumin and<jats:italic>R. Damascena<\/jats:italic>extract in the creation of the peel\u2010off mask gel ensures its efficacy and safety for skin application.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jocd.16255","type":"journal-article","created":{"date-parts":[[2024,2,26]],"date-time":"2024-02-26T10:03:41Z","timestamp":1708941821000},"page":"2156-2169","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Formulation and evaluation of antioxidant and antibacterial activity of a peel\u2010off facial masks moisturizer containing curcumin and<i>Rosa Damascena<\/i>extract"],"prefix":"10.1111","volume":"23","author":[{"given":"Mohammad Mehdi","family":"Nemati","sequence":"first","affiliation":[{"name":"Pharmaceutical Sciences Research Center Shiraz University of Medical Sciences Shiraz Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3405-511X","authenticated-orcid":false,"given":"Mehdi","family":"Abedi","sequence":"additional","affiliation":[{"name":"Pharmaceutical Sciences Research Center Shiraz University of Medical Sciences Shiraz Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Younes","family":"Ghasemi","sequence":"additional","affiliation":[{"name":"Pharmaceutical Sciences Research Center Shiraz University of Medical Sciences Shiraz Iran"},{"name":"Department of Pharmaceutical Biotechnology Shiraz University of Medical Sciences Shiraz Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hajar","family":"Ashrafi","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutics, School of Pharmacy Shiraz University of Medical Sciences Shiraz Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2680-2581","authenticated-orcid":false,"given":"Mobin","family":"Haghdel","sequence":"additional","affiliation":[{"name":"Department of Tissue Engineering, School of Advanced Medical Sciences and Technologies Shiraz University of Medical Sciences Shiraz Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,2,26]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.22373\/lj.v9i1.10206"},{"issue":"4","key":"e_1_2_9_3_1","first-page":"333","article-title":"Preparation and evaluation of herbal peel off face mask","volume":"5","author":"Dariska CSK","year":"2015","journal-title":"Am J PharmTech Res"},{"key":"e_1_2_9_4_1","first-page":"159","article-title":"Development of cosmetic mask formulations","volume":"40","author":"Baby AR","year":"2004","journal-title":"Revista Brasileira de Ci\u00eancias Farmac\u00eauticas"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1208\/s12249-013-9930-8"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.4172\/2153-2435.1000e168"},{"issue":"4","key":"e_1_2_9_7_1","first-page":"295","article-title":"Pharmacological effects of rosa damascena","volume":"14","author":"Boskabady MH","year":"2011","journal-title":"Iran J Basic Med Sci"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fct.2008.11.036"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.3923\/ijp.2007.187.190"},{"issue":"2","key":"e_1_2_9_10_1","first-page":"55","article-title":"The ulcer protective and anti\u2010inflammatory effect of Bulgarian rose oil","volume":"11","author":"Maleev A","year":"1972","journal-title":"Eksp Med Morfol"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/53.1.247S"},{"issue":"2","key":"e_1_2_9_12_1","first-page":"163","article-title":"Analgesic and anti\u2010inflammatory effects of Rosa damascena hydroalcoholic extract and its essential oil in animal models","volume":"9","author":"Hajhashemi V","year":"2010","journal-title":"Iran J Pharm Res"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11746-009-1483-3"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.2310\/6620.2011.10118"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.12145"},{"key":"e_1_2_9_16_1","first-page":"134","article-title":"Synergistic effects of plant wxtracts and antibiotics on Staphylococcus aureus strains isolated from clinical specimens","volume":"3","author":"Adwan G","year":"2008","journal-title":"Middle\u2010East J Sci Res"},{"key":"e_1_2_9_17_1","unstructured":"LisinG SafiyevS CrakerL.Antimicrobial activity of some essential oils. 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