{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T01:33:06Z","timestamp":1747186386974,"version":"3.40.5"},"reference-count":15,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2024,4,12]],"date-time":"2024-04-12T00:00:00Z","timestamp":1712880000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Cosmetic Dermatology"],"published-print":{"date-parts":[[2024,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>We previously demonstrated a possible therapeutic benefit of VFEM (variable frequency electromagnetic energy) technology for the treatment of Post Treatment Lyme Disease Syndrome (PTLDS) or Chronic Lyme Disease (CLD). As a result, we prospectively enrolled 10 patients, all having significant debility, to determine to what extent we could improve their quality of life. Eight patients completed the 10 treatments.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>All eight patients had a significant improvement in quality of life within a 4\u2010month time frame.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>VFEM is a stand\u2010alone modality that appears to demonstrate a significant improvement in quality of life in PTLDS or CLD with little or no risk or side effects of treatment.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jocd.16256","type":"journal-article","created":{"date-parts":[[2024,4,13]],"date-time":"2024-04-13T05:39:31Z","timestamp":1712986771000},"page":"2044-2048","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["A prospective study of patients with post treatment Lyme disease syndrome treated with modified VFEM energy"],"prefix":"10.1111","volume":"23","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-8261-005X","authenticated-orcid":false,"given":"Gregory P.","family":"Derderian","sequence":"first","affiliation":[{"name":"Michigan Vascular Institute  Birmingham Michigan USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicole","family":"Otenbaker","sequence":"additional","affiliation":[{"name":"Michigan Vascular Institute  Birmingham Michigan USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,4,12]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13071-019-3495-7"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.idc.2007.12.013"},{"issue":"5","key":"e_1_2_10_4_1","first-page":"4031","article-title":"Antimicrobial effects of electromagnetic fields: a review of current techniques and mechanisms of action","volume":"8","author":"Yadollahpour A","year":"2014","journal-title":"J Pure Appl Microbiol"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/s1567-5394(01)00152-9"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bioelechem.2003.11.010"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1080\/15368370500379715"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.micron.2009.06.009"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12013-008-9020-9"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00284-010-9811-2"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1140\/epjnbp12"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/bem.20391"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.3390\/app11167760"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.2139\/ssrn.4047045"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.3389\/fmed.2019.00283"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.2147\/IJGM.S140224"}],"container-title":["Journal of Cosmetic Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jocd.16256","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,18]],"date-time":"2024-05-18T15:18:28Z","timestamp":1716045508000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jocd.16256"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,4,12]]},"references-count":15,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2024,6]]}},"alternative-id":["10.1111\/jocd.16256"],"URL":"https:\/\/doi.org\/10.1111\/jocd.16256","archive":["Portico"],"relation":{},"ISSN":["1473-2130","1473-2165"],"issn-type":[{"type":"print","value":"1473-2130"},{"type":"electronic","value":"1473-2165"}],"subject":[],"published":{"date-parts":[[2024,4,12]]},"assertion":[{"value":"2023-12-02","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-02-18","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-04-12","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}