{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T03:05:48Z","timestamp":1782443148820,"version":"3.54.5"},"reference-count":35,"publisher":"Wiley","issue":"S1","license":[{"start":{"date-parts":[[2024,4,8]],"date-time":"2024-04-08T00:00:00Z","timestamp":1712534400000},"content-version":"vor","delay-in-days":7,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Cosmetic Dermatology"],"published-print":{"date-parts":[[2024,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Scarring is one of the most prevalent long\u2010term complications of acne vulgaris and has cosmetic, psychological, and social burdens. Contemporary management programs integrate multiple modalities to best address the multiple factors underlying their development and persistence. This work assessed the impact of sequential multimodal laser therapy on acne scar geometrics and texture.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Adult patients (<jats:italic>n<\/jats:italic>\u2009=\u200916) with Fitzpatrick skin type II\u2013IV and presenting with facial acne scars, underwent three combination ablative (CO<jats:sub>2<\/jats:sub>), and nonablative (1570\u2009nm) laser treatment sessions at two\u2010month intervals. Treatment was delivered using a ProScan Hybrid applicator, with each regimen including illumination with both ablative and a nonablative lasers applied in a grid mode sequence. Scar microtopography was assessed at baseline and 6\u2009months after the last treatment session.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>At baseline, all patients had both box and rolling scars, while only three had icepick scars. Six months following treatment, mean scar volume improved from 5.7\u2009\u00b1\u20095.2\u2009mm<jats:sup>3<\/jats:sup> at baseline to 3.1\u2009\u00b1\u20093.0\u2009mm<jats:sup>3<\/jats:sup> and mean affected area improved from 165.6\u2009\u00b1\u2009134.0\u2009mm<jats:sup>2<\/jats:sup> 94.0\u2009\u00b1\u200980.1\u2009mm<jats:sup>2<\/jats:sup>, translating to 47.0\u2009\u00b1\u20097.9% and 43.2\u2009\u00b1\u20098.6% reductions from baseline, respectively. Patients were highly satisfied with treatment outcomes, and no serious adverse reactions were documented during the course of treatment or follow\u2010up.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Multimodal CO<jats:sub>2<\/jats:sub> and 1570\u2010nm laser treatment improved the surface profilometry of patients with atrophic facial acne scars. Customization of both treatment intervals and laser settings to cosmetic regions, scar profiles and skin phototypes may further enhance treatment outcomes and expand its applicability to additional skin deformities.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jocd.16283","type":"journal-article","created":{"date-parts":[[2024,4,8]],"date-time":"2024-04-08T12:04:51Z","timestamp":1712577891000},"page":"13-18","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Resurfacing of atrophic facial acne scars with a multimodality CO<sub>2<\/sub> and 1570\u2009nm laser system"],"prefix":"10.1111","volume":"23","author":[{"given":"Pablo Naranjo","family":"Garc\u00eda","sequence":"first","affiliation":[{"name":"Elite Laser Clinic  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rodolfo Lopez","family":"Andrino","sequence":"additional","affiliation":[{"name":"Elite Laser Clinic  Madrid 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