{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T05:28:14Z","timestamp":1790659694094,"version":"4.1.0"},"reference-count":13,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2024,4,1]],"date-time":"2024-04-01T00:00:00Z","timestamp":1711929600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Cosmetic Dermatology"],"published-print":{"date-parts":[[2024,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Micronized acellular dermal matrix (mADM) can induce tissue regeneration and repair, and filling.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>The efficacy and safety of (mADM) were evaluated in the treatment of atrophic acne scar.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>In this single\u2010blinded, self\u2010controlled, split\u2010face study, 16 patients (48 scar sites) were divided into treatment group (24 scar sites) and control group (24 scar sites). One side of the affected area was treated with mADM combined with platelet rich plasma (PRP) injection as the treatment group; the other side of the affected area was treated with PRP injection as the control group. The efficacy was evaluated by the Acne scar assessment scale (ASAS) and Acne Scar Weight Rating Scale (ECCA) 3\u2009months after treatment.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>After 3\u2010month treatment in 16 patients, the atrophic acne scars in both groups were all improved. The ASAS score and ECCA weight score in the treatment group was significantly lower than that in the control group (2.50\u2009\u00b1\u20090.51 vs. 3.62\u2009\u00b1\u20090.77 and 14.17\u2009\u00b1\u200910.18 vs. 31.88\u2009\u00b1\u200913.25; <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001).<\/jats:p><\/jats:sec><jats:sec><jats:title>Limitations<\/jats:title><jats:p>Short\u2010term 3\u2010month treatment period. Small sample size limits generalizability of results.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The curative effect of mADM combined with PRP is significantly better than that of PRP alone.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jocd.16293","type":"journal-article","created":{"date-parts":[[2024,4,1]],"date-time":"2024-04-01T10:19:14Z","timestamp":1711966754000},"page":"2386-2391","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Micronized acellular dermal matrix combined with platelet rich plasma in the treatment of atrophic acne scars: A self\u2010controlled split face study"],"prefix":"10.1111","volume":"23","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-9378-3029","authenticated-orcid":false,"given":"Sunwoo","family":"Park","sequence":"first","affiliation":[{"name":"Aesthetic Plastic Surgery Department, Dermatology Hospital Southern Medical University  Guangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lining","family":"Huang","sequence":"additional","affiliation":[{"name":"Aesthetic Department, Dermatology Hospital Southern Medical University  Guangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xian","family":"Ao","sequence":"additional","affiliation":[{"name":"Aesthetic Plastic Surgery Department, Dermatology Hospital Southern Medical University  Guangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amira","family":"Elbendary","sequence":"additional","affiliation":[{"name":"Dermatology Department, Kasr Alainy Faculty of Medicine Cairo University  Giza Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0640-5899","authenticated-orcid":false,"given":"Guomin","family":"Li","sequence":"additional","affiliation":[{"name":"Dermatology Department, Dermatology Hospital Southern Medical University  Guangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hua","family":"Xian","sequence":"additional","affiliation":[{"name":"Aesthetic Plastic Surgery Department, Dermatology Hospital Southern Medical University  Guangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meiyi","family":"Du","sequence":"additional","affiliation":[{"name":"Aesthetic Department, Dermatology Hospital Southern Medical University  Guangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruzeng","family":"Xue","sequence":"additional","affiliation":[{"name":"Dermatology Department, Dermatology Hospital Southern Medical University  Guangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chunmei","family":"Wang","sequence":"additional","affiliation":[{"name":"Aesthetic Plastic Surgery Department, Dermatology Hospital Southern Medical University  Guangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,4]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1155\/2010\/893080"},{"issue":"5","key":"e_1_2_11_3_1","first-page":"33","article-title":"Effective treatments of atrophic acne scars","volume":"8","author":"Gozali MV","year":"2015","journal-title":"J Clin Aesthet Dermatol"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-4725.2011.02036.x"},{"issue":"1","key":"e_1_2_11_5_1","first-page":"2873","article-title":"What happens to an acellular dermal matrix after implantation in the human body? A histological and electron microscopic study","volume":"62","author":"Boh\u00e1\u010d M","year":"2018","journal-title":"Eur J Histochem"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/DSS.0000000000001872"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/DSS.0000000000001863"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1039\/C9RA03736E"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10561-011-9245-5"},{"issue":"19","key":"e_1_2_11_10_1","first-page":"3675","article-title":"Decellularization of tissues and organs","volume":"27","author":"Gilbert TW","year":"2006","journal-title":"Biomaterials"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1001\/archfaci.2.2.130"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/1097-4636(2001)58:1<10::AID-JBM20>3.0.CO;2-E"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-2004-861753"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/jocd.12981"}],"container-title":["Journal of Cosmetic Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jocd.16293","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,6,20]],"date-time":"2024-06-20T02:23:28Z","timestamp":1718850208000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jocd.16293"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,4]]},"references-count":13,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2024,7]]}},"alternative-id":["10.1111\/jocd.16293"],"URL":"https:\/\/doi.org\/10.1111\/jocd.16293","archive":["Portico"],"relation":{},"ISSN":["1473-2130","1473-2165"],"issn-type":[{"value":"1473-2130","type":"print"},{"value":"1473-2165","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,4]]},"assertion":[{"value":"2023-10-24","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-03-11","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-04-01","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}