{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T19:00:51Z","timestamp":1791399651925,"version":"4.3.3"},"reference-count":36,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2024,4,8]],"date-time":"2024-04-08T00:00:00Z","timestamp":1712534400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Cosmetic Dermatology"],"published-print":{"date-parts":[[2024,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>The human lip vermilion, also known as the red lip, is important to the quality of life and has long attracted the attention of cosmetic researchers. However, there is limited existing literature on the physiological characteristics and age\u2010related alterations in the human vermilion.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>We aim to provide an overview of the physiological characteristics and age\u2010related alterations in the human vermilion.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This article is a result of previous research. We conducted a literature search using various academic databases such as Google Scholar, Web of Science, and PubMed. Our findings provided a comprehensive understanding of the physiological characteristics and age\u2010related changes of the human lip vermilion.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The human lip vermilion has a unique structure and physiological characteristics, and during the aging process, a few changes may occur in the human lip vermilion.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Understanding the human lip vermilion's physiological characteristics and age\u2010related changes can provide key information for the future innovation of lip vermilion care products. Further investigations are necessary to reach a consensus on the physiological characteristics and age\u2010related alterations in the human vermilion.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jocd.16317","type":"journal-article","created":{"date-parts":[[2024,4,9]],"date-time":"2024-04-09T01:40:52Z","timestamp":1712626852000},"page":"2676-2680","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Human lip vermilion: Physiology and age\u2010related changes"],"prefix":"10.1111","volume":"23","author":[{"given":"Jianli","family":"Shang","sequence":"first","affiliation":[{"name":"Beijing Underproved Medical Technology Co., LTD  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoyue","family":"Feng","sequence":"additional","affiliation":[{"name":"Beijing Underproved Medical Technology Co., LTD  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0899-5519","authenticated-orcid":false,"given":"Yong","family":"Chen","sequence":"additional","affiliation":[{"name":"Beijing Underproved Medical Technology Co., LTD  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhengping","family":"Gu","sequence":"additional","affiliation":[{"name":"Beijing Underproved Medical Technology Co., LTD  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Youting","family":"Liu","sequence":"additional","affiliation":[{"name":"Beijing Underproved Medical Technology Co., LTD  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,4,8]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.a.32602"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.13189\/ojdom.2015.030104"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/srt.12814"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms21082807"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.3390\/anatomia1010002"},{"issue":"7","key":"e_1_2_10_7_1","first-page":"840","article-title":"Translabial route: a novelistic platform for systemic drug delivery","volume":"4","author":"Bhairy S","year":"2016","journal-title":"Int J Innovative Pharm Sci Res"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/ics.12038"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2133.2003.05741.x"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s004030050453"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.actbio.2022.11.031"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10735-021-10016-y"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.4103\/njms.NJMS_15_20"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.archoralbio.2004.09.012"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1080\/02713680802485147"},{"issue":"12","key":"e_1_2_10_16_1","first-page":"44","article-title":"Clinical assessment of a combination lip treatment to restore moisturization and fullness","volume":"2","author":"Trookman NS","year":"2009","journal-title":"J Clin Aesthet Dermatol"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdermsci.2017.11.006"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chemphyslip.2021.105055"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/ics.12677"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdermsci.2021.07.008"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00403-012-1286-5"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/ics.12335"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/dth.14695"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-2007-997764"},{"issue":"2","key":"e_1_2_10_25_1","first-page":"109","article-title":"Les grains de Fordyce: maladie, h\u00e9t\u00e9rotopie ou ad\u00e9nome? 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