{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T16:52:34Z","timestamp":1790959954739,"version":"4.1.0"},"reference-count":27,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2024,4,15]],"date-time":"2024-04-15T00:00:00Z","timestamp":1713139200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003052","name":"Ministry of Trade, Industry and Energy","doi-asserted-by":"publisher","award":["20024946"],"award-info":[{"award-number":["20024946"]}],"id":[{"id":"10.13039\/501100003052","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Cosmetic Dermatology"],"published-print":{"date-parts":[[2024,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Enoxolone, derived from licorice, possesses potent anti\u2010inflammatory, and antioxidant properties. However, its effectiveness in alleviating post\u2010laser reactions has not been extensively studied.<\/jats:p><\/jats:sec><jats:sec><jats:title>Aims<\/jats:title><jats:p>This randomized split\u2010face pilot study aimed to evaluate the effects of enoxolone on skin following laser treatment.<\/jats:p><\/jats:sec><jats:sec><jats:title>Patients\/Methods<\/jats:title><jats:p>Ten healthy subjects underwent non\u2010ablative 1550\u2009nm Er:Glass fractional laser treatment and then randomly applied a moisturizer without enoxolone on one side of the face and a dermo\u2010cosmetic formular containing 2% enoxolone mixed with the same moisturizer on the other side. The erythema index (EI), clinician's erythema assessment (CEA), and pain scores were recorded at 30\u2009min, 60\u2009min, and 24\u2009h posttreatment.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The group treated with enoxolone showed significantly lower EI and CEA compared to the control group at 24\u2009h posttreatment. Additionally, pain scores were notably reduced in the enoxolone\u2010treated group 30\u2009min after treatment.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>This study suggests that dermo\u2010cosmetic formular containing 2% enoxolone is effective in reducing erythema and pain following laser treatment.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jocd.16329","type":"journal-article","created":{"date-parts":[[2024,4,16]],"date-time":"2024-04-16T06:44:45Z","timestamp":1713249885000},"page":"2657-2662","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["The efficacy of enoxolone in reducing erythema and pain after laser treatment: A randomized split\u2010face pilot study"],"prefix":"10.1111","volume":"23","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0248-7708","authenticated-orcid":false,"given":"Sun Young","family":"Choi","sequence":"first","affiliation":[{"name":"Department of Dermatology 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