{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,10]],"date-time":"2026-06-10T22:26:34Z","timestamp":1781130394560,"version":"3.54.1"},"reference-count":37,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2024,6,28]],"date-time":"2024-06-28T00:00:00Z","timestamp":1719532800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2024,6,28]],"date-time":"2024-06-28T00:00:00Z","timestamp":1719532800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Cosmetic Dermatology"],"published-print":{"date-parts":[[2024,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To assess the effectiveness and safety of treating erythematotelangiectatic rosacea using fractional radiofrequency (FRF).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Twenty patients with a confirmed diagnosis of erythema capillaris rosacea were selected, and one side of each patient's face was randomly assigned to receive FRF treatments for three to six times, with an interval of 2\u2009weeks between each treatment. VISIA, dermoscopy, and the Clinician's Erythema Evaluation Scale (CEA) were applied to evaluate the efficacy of the treatment before and after the treatment, to record the VAS scores and adverse reactions, and to conduct a patient satisfaction survey.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The characteristic counts and scores of red zone and porphyrin as assessed by VISIA test were significantly decreased, and the difference between the treated side and the pretreatment side was statistically significant (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.05), and the efficacy of the treatment was statistically insignificant compared with the control side, except for the red zone and porphyrin which were statistically significant before and after the treatment (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&gt;\u20090.05). By CEA score, the difference between the treated side after treatment and the control side was statistically significant (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.05), and the difference between the treated side before and after treatment was statistically significant (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.05); the difference between the control side before and after treatment was not statistically significant (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&gt;\u20090.05). Dermatoscopic observation showed reduction in pore size, reduction of yellowish\u2010white and black horn plugs within the pores, lightening of the red background and thinning and blurring of the capillary structure on the treated side of the skin compared to the control side, and the skin on the treated side showed the above mentioned changes before and after the treatment as well. The mean pain score of the subjects was obtained by VAS score 3.67\u2009\u00b1\u20090.90. Adverse effects included mild edema, erythema, and microscopic crusting; no long\u2010term adverse effects were seen in all patients. The efficacy of FRF treatment was evaluated 1\u2009month after the final treatment, and 85% of the subjects rated it as satisfactory, very satisfactory, and very satisfactory.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>FRF for the treatment of erythematous capillary dilatation rosacea is effective, safe, and suitable for clinical promotion.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jocd.16354","type":"journal-article","created":{"date-parts":[[2024,6,29]],"date-time":"2024-06-29T01:41:09Z","timestamp":1719625269000},"page":"2895-2904","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Efficacy\u00a0of fractional radiofrequency in the treatment of erythematous capillary rosacea: A split\u2010face study"],"prefix":"10.1111","volume":"23","author":[{"given":"Dongqing","family":"Li","sequence":"first","affiliation":[{"name":"Department of Dermatology, Qujing Hospital Kunming Medical University  Qujing Yunnan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yujing","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Dermatology, The First Affiliated Hospital Kunming Medical University  Kunming Yunnan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhi","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Dermatology, The First Affiliated Hospital Kunming Medical University  Kunming Yunnan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiaoyu","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Dermatology, The First Affiliated Hospital Kunming Medical University  Kunming Yunnan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dengrong","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Dermatology, The First Affiliated Hospital Kunming Medical University  Kunming Yunnan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jinlai","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Dermatology, The First Affiliated Hospital Kunming Medical University  Kunming Yunnan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haojun","family":"Xiong","sequence":"additional","affiliation":[{"name":"Department of Dermatology, The First Affiliated Hospital Kunming Medical University  Kunming Yunnan China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,6,28]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.16481"},{"issue":"7","key":"e_1_2_8_3_1","first-page":"489","article-title":"Rosacea: clinical features and lassification","volume":"64","author":"Lehmannn P","year":"2013","journal-title":"Hautarzt"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2004.03.030"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/jocd.12903"},{"key":"e_1_2_8_6_1","first-page":"621","article-title":"A possible role for non\u2010ablative radiofrequency in the treatment of rosacea","volume":"2","author":"Ruiz\u2010Esparza J","year":"2003","journal-title":"J Drugs Dermatol"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10103-015-1850-2"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-4725.2012.02547.x"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1524-4725.2003.29081.x"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-4725.2010.01510.x"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/exd.14115"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2014.05.044"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMcp1506630"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1097\/DSS.0000000000000968"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/DSS.0000000000002009"},{"issue":"8","key":"e_1_2_8_16_1","first-page":"1","article-title":"Efficacy and safety of non\u2010surgical short\u2010wave radiofrequency treatment of mild\u2010to\u2010moderate erythematotelangiectatic rosacea:a pro\u2010spective,open\u2010label pilot study","volume":"16","author":"Wang B","year":"2021","journal-title":"Arch Dermatol Res"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.23453"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.DSS.0000452625.01889.c3"},{"issue":"4","key":"e_1_2_8_19_1","first-page":"562","article-title":"Porphyrin metabolisms in human skin commensal Propionibacterium acnes bacteria: potential application to monitor human radiation risk","volume":"20","author":"Shu M","year":"2013","journal-title":"Curr Med Chem"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(11)60321-8"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1038\/jid.2013.21"},{"issue":"9","key":"e_1_2_8_22_1","first-page":"1","article-title":"Antibiotic resistance in acne treatment","volume":"17","author":"Humphrey S","year":"2012","journal-title":"Skin Therapy Lett"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/1346-8138.12483"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.14714"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1111\/jocd.13299"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.1111\/1346-8138.12471"},{"key":"e_1_2_8_27_1","doi-asserted-by":"publisher","DOI":"10.1080\/14764170410008124"},{"key":"e_1_2_8_28_1","doi-asserted-by":"publisher","DOI":"10.3109\/14764172.2012.687824"},{"key":"e_1_2_8_29_1","doi-asserted-by":"publisher","DOI":"10.3109\/14764172.2011.606467"},{"key":"e_1_2_8_30_1","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.22071"},{"key":"e_1_2_8_31_1","doi-asserted-by":"publisher","DOI":"10.3109\/14764172.2012.699682"},{"key":"e_1_2_8_32_1","first-page":"144","article-title":"Fractional ablative radio\u2010frequency resurfacing in Asian and caucasian skin: a novel method for deep radiofrequency fractional skin rejuvenation","volume":"2","author":"Stephen R","year":"2012","journal-title":"J Cosmet Dermatol Sci Appl"},{"key":"e_1_2_8_33_1","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.22420"},{"key":"e_1_2_8_34_1","doi-asserted-by":"publisher","DOI":"10.1111\/jocd.12195"},{"key":"e_1_2_8_35_1","doi-asserted-by":"publisher","DOI":"10.1111\/dsu.12470"},{"key":"e_1_2_8_36_1","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.23369"},{"key":"e_1_2_8_37_1","doi-asserted-by":"publisher","DOI":"10.1001\/archfaci.10.4.238"},{"key":"e_1_2_8_38_1","doi-asserted-by":"publisher","DOI":"10.1097\/00006534-200201000-00048"}],"container-title":["Journal of Cosmetic Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jocd.16354","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/jocd.16354","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jocd.16354","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,16]],"date-time":"2026-05-16T06:56:32Z","timestamp":1778914592000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jocd.16354"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,6,28]]},"references-count":37,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2024,9]]}},"alternative-id":["10.1111\/jocd.16354"],"URL":"https:\/\/doi.org\/10.1111\/jocd.16354","archive":["Portico"],"relation":{},"ISSN":["1473-2130","1473-2165"],"issn-type":[{"value":"1473-2130","type":"print"},{"value":"1473-2165","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,6,28]]},"assertion":[{"value":"2024-02-08","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-04-02","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-06-28","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}