{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T00:52:17Z","timestamp":1791507137278,"version":"4.3.4"},"reference-count":26,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2024,5,27]],"date-time":"2024-05-27T00:00:00Z","timestamp":1716768000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2024,5,27]],"date-time":"2024-05-27T00:00:00Z","timestamp":1716768000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100013254","name":"National College Students Innovation and Entrepreneurship Training Program","doi-asserted-by":"publisher","award":["202210367015"],"award-info":[{"award-number":["202210367015"]}],"id":[{"id":"10.13039\/501100013254","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100009558","name":"University Natural Science Research Project of Anhui Province","doi-asserted-by":"publisher","award":["2022AH051451"],"award-info":[{"award-number":["2022AH051451"]}],"id":[{"id":"10.13039\/501100009558","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100009558","name":"University Natural Science Research Project of Anhui Province","doi-asserted-by":"publisher","award":["KJ2021A0772"],"award-info":[{"award-number":["KJ2021A0772"]}],"id":[{"id":"10.13039\/501100009558","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Cosmetic Dermatology"],"published-print":{"date-parts":[[2024,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Patients with hypertrophic scarring tend to experience recurrence after treatment, which often occurs in areas of the body with high skin tension.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>To evaluate better treatments aimed at reducing the risk of scar recurrence in areas of high skin tension.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      Patients were randomly divided into the following three treatment groups: botulinum toxin type A (BTA) via dual\u2010plane micro\u2010drop injections, triamcinolone acetonide (TAC) suspension, and CO\n                      <jats:sub>2<\/jats:sub>\n                      via fractional CO\n                      <jats:sub>2<\/jats:sub>\n                      laser. Interventions were implemented in all three groups once a month for three consecutive sessions. After the final treatment, scarring was evaluated at 1, 3, 6, 12, and 24\u2009months using the Patient and Observer Scar Assessment Scale (POSAS).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The 3\u2010month POSAS score for each scar indicator in the treatment groups was significantly lower than that in the preoperative groups (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). The scar score in the TAC group decreased at 3\u2009months and increased thereafter. For other groups, the scar score continually decreased at all time points according to the Patient Scar Assessment Scale. Based on the Observer Scar Assessment Scale, the scar score continuously decreased at all time points in the BTA group; in the TAC group, it decreased at 1\u2009month and increased thereafter; and in the CO\n                      <jats:sub>2<\/jats:sub>\n                      group, the scar score decreased at 3\u2009months and subsequently stabilized.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>All three treatment methods were effective. However, the BTA group experienced a reduced risk of scar recurrence and maintained long\u2010term treatment effects.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jocd.16401","type":"journal-article","created":{"date-parts":[[2024,5,28]],"date-time":"2024-05-28T00:39:49Z","timestamp":1716856789000},"page":"3182-3188","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Comparison of dual\u2010plane micro\u2010drop injection of botulinum toxin type A with two traditional methods for treating hypertrophic scars in the tension zone: A long\u2010term clinical application study"],"prefix":"10.1111","volume":"23","author":[{"given":"Banghong","family":"Jiang","sequence":"first","affiliation":[{"name":"Department of Plastic Surgery 1st Affiliated Hospital of Bengbu Medical College  Bengbu Anhui province 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