{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T00:52:20Z","timestamp":1791507140212,"version":"4.3.4"},"reference-count":29,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2024,6,19]],"date-time":"2024-06-19T00:00:00Z","timestamp":1718755200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2024,6,19]],"date-time":"2024-06-19T00:00:00Z","timestamp":1718755200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Cosmetic Dermatology"],"published-print":{"date-parts":[[2024,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>\n                      Titanium dioxide (TiO\n                      <jats:sub>2<\/jats:sub>\n                      ), a white powder, represents the opacifier used in many products, including drugs, foods, cosmetics, paints, and dyes.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Method<\/jats:title>\n                    <jats:p>\n                      The Uv\u2010Vis spectrophotometry was a particularly suitable technique to quantify TiO\n                      <jats:sub>2<\/jats:sub>\n                      in the solutions obtained from cosmetics. In this work, we determined the TiO\n                      <jats:sub>2<\/jats:sub>\n                      content in a total of 88 samples of eye shadows and face powders of different brands and costs. Before to analyse the samples, we developed the mineralization and analysis method, in fact, fusion with potassium bisulphate would be very laborious because it must be carried out on one sample at a time and requires very long times, instead, the mineralization with the acid mixture and the aid of microwaves allowed us to solubilize six samples at the same time within 45\u2009min.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      From the results obtained, we can state that the highest concentrations of TiO\n                      <jats:sub>2<\/jats:sub>\n                      are found in the eyeshadows with a maximum value of 36% in a blue eyeshadow.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jocd.16422","type":"journal-article","created":{"date-parts":[[2024,6,20]],"date-time":"2024-06-20T01:49:36Z","timestamp":1718848176000},"page":"3388-3394","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Titanium dioxide in face powders and eyeshadows: Developing an analytical methodology for accessing customer safety"],"prefix":"10.1111","volume":"23","author":[{"given":"Diana","family":"Amorello","sequence":"first","affiliation":[{"name":"Department of Science and Technology Biological, Chemical and Pharmaceutical University of Palermo  Palermo Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marzia","family":"Ferrara","sequence":"additional","affiliation":[{"name":"Department of Science and Technology Biological, Chemical and Pharmaceutical University of Palermo  Palermo Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Santino","family":"Orecchio","sequence":"additional","affiliation":[{"name":"Department of Science and Technology Biological, Chemical and Pharmaceutical University of Palermo  Palermo Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,6,19]]},"reference":[{"key":"e_1_2_7_2_1","unstructured":"Gazzetta ufficiale dell'Unione Europea(22.12.2009) L 342\/59 REGOLAMENTO (CE) n. 1223\/2009 DEL PARLAMENTO EUROPEO E DEL CONSIGLIO del 30 novembre 2009 sui prodotti cosmetici."},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.annder.2020.04.027"},{"key":"e_1_2_7_4_1","unstructured":"Rapporti ISTISAN 19\/24; Istituto Superiore Sanit\u00e0.2019."},{"key":"e_1_2_7_5_1","volume-title":"Metalli in prodotti cosmetici: procedure raccomandate per la determinazione e valutazione dei rischi per la salute","author":"Alimonti A","year":"2009"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.microc.2016.03.008"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1080\/15287394.2015.1021433"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.microc.2016.09.010"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.4490\/ijerph14020195"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.microc.2013.11.015"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/slct.202300986"},{"key":"e_1_2_7_12_1","unstructured":"https:\/\/www.cosmeticaitalia.it\/centro\u2010studi\/Beauty\u2010Report\u20102019\/"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jsps.2020.05.006"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1080\/15275922.2018.1448908"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1080\/02772248.2011.582040"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.yrtph.2014.02.003"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.3390\/cosmetics5040057"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12951-018-0376-8"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1179\/135100001101536463"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tox.2005.05.007"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpharm.2022.121550"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jfca.2023.105541"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1002\/slct.202300200"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jfca.2023.105541"},{"key":"e_1_2_7_25_1","unstructured":"SelleriR Botr\u00e8C OrzalesiG.Chimica e tecnologia dei prodotti cosmetici.197737. 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Website ECHA echa.europa.eu\/it\/registry\u2010of\u2010clh\u2010intentions\u2010until\u2010outcome\/\u2212\/dislist\/details\/0b0236e18075da 38"},{"key":"e_1_2_7_27_1","unstructured":"Scientific Committee On Consumer Safety (SCCS).Request for a scientific opinion on Titanium dioxide (TiO2) (CAS\/EC numbers 13463\u201367\u20107\/236\u2013675\u20105 1317\u201070\u20100\/215\u2013280\u20101 1317\u201080\u20102\/215\u2013282\u20102) used in cosmetic products."},{"key":"e_1_2_7_28_1","unstructured":"Regolamento (CE) n.1223\/2009 del Parlamento europeo e del Consiglio del 30 novembre 2009 sui prodotti cosmetici."},{"key":"e_1_2_7_29_1","unstructured":"MendhamJ DenneyRC BarnesD ThomasMJK eds.Vogel's Textbook of Quantitative chemical analysis.1995."},{"key":"e_1_2_7_30_1","unstructured":"HollerFJ CrouchSR.Fondamenti di Chimica Analitica di Skoog e West.2015."}],"container-title":["Journal of Cosmetic Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jocd.16422","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/jocd.16422","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jocd.16422","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T00:48:36Z","timestamp":1791506916000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jocd.16422"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,6,19]]},"references-count":29,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2024,10]]}},"alternative-id":["10.1111\/jocd.16422"],"URL":"https:\/\/doi.org\/10.1111\/jocd.16422","archive":["Portico"],"relation":{},"ISSN":["1473-2130","1473-2165"],"issn-type":[{"value":"1473-2130","type":"print"},{"value":"1473-2165","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,6,19]]},"assertion":[{"value":"2023-12-05","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-05-29","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-06-19","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}