{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T00:52:18Z","timestamp":1791507138459,"version":"4.3.4"},"reference-count":25,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Cosmetic Dermatology"],"published-print":{"date-parts":[[2024,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Excess body adiposity and skin irregularities represent a major problem in today's society. Currently, radiofrequency\u2010based devices constitute an increasingly popular medical\u2010aesthetic application and a powerful non\u2010invasive method to combat this problem.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>This study aims to determine the efficacy and safety of the high\u2010frequency device Zionic\u2122 (Termosalud, Inc., Gij\u00f3n, Spain) in reducing body contouring and improving skin appearance in the abdomen\/flanks or thighs.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods<\/jats:title>\n                    <jats:p>Thirty nine individuals were treated with the Zionic\u2122 device in the abdomen\/flanks or thighs. A total of 8 sessions of 40\u201350\u2009min each, 72\/96\u2009h apart were performed. At baseline, body measurements were taken including photographs, body contours, and ultrasound scans to assess dermal thickness, dermal echogenicity, and subcutaneous fat thickness. The measurements were repeated after the eight sessions for comparison and analysis. Quantitative data was complemented with a customized survey to evaluate participants satisfaction level.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>At the follow\u2010up visit, a significant average reduction of 3% in abdomen\/flanks circumferences and 2% in thighs contours was noticed. Abdomen\/flanks and thighs subcutaneous fat layer thickness was significantly reduced by 8% and 6%, respectively. Dermal echogenicity changes, related to skin collagen content and organization, showed non\u2010significant increasing tendencies of 7% for abdomen\/flanks and 8% for thighs. Thighs dermal thickness was significantly increased by 6%. Results were associated to a high satisfaction level (80%) and no severe adverse events.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Zionic\u2122 treatment is a safe, effective, and well\u2010tolerated noninvasive procedure for body contouring and improvement of skin properties in abdomen, flanks, and thighs.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jocd.16431","type":"journal-article","created":{"date-parts":[[2024,7,2]],"date-time":"2024-07-02T01:55:51Z","timestamp":1719885351000},"page":"3263-3271","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Rotational radiofrequency\u2010based technology leads to adipose tissue reduction and contouring effect in the thighs, abdomen, and flanks"],"prefix":"10.1111","volume":"23","author":[{"ORCID":"https:\/\/orcid.org\/0009-0003-2839-7687","authenticated-orcid":false,"given":"Alejandra Fern\u00e1ndez","family":"Santos","sequence":"first","affiliation":[{"name":"Termosalud SL  Gij\u00f3n Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alejandra Iglesias","family":"Fern\u00e1ndez","sequence":"additional","affiliation":[{"name":"Termosalud SL  Gij\u00f3n Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lorena Su\u00e1rez","family":"Fern\u00e1ndez","sequence":"additional","affiliation":[{"name":"Termosalud SL  Gij\u00f3n Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9942-1144","authenticated-orcid":false,"given":"Leticia Huergo","family":"Zapico","sequence":"additional","affiliation":[{"name":"Termosalud SL  Gij\u00f3n Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susana Valero","family":"Freitag","sequence":"additional","affiliation":[{"name":"Termosalud SL  Gij\u00f3n Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,7,1]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.22223"},{"issue":"503","key":"e_1_2_11_3_1","first-page":"vii","article-title":"Noninvasive body contouring with radiofrequency, ultrasound, cryolipolysis, and low\u2010level laser therapy","volume":"38","author":"Mulholland RS","year":"2011","journal-title":"Clin Plast Surg"},{"key":"e_1_2_11_4_1","unstructured":"Rolling Meadows.Skin Experts.2021https:\/\/asds.net"},{"issue":"1","key":"e_1_2_11_5_1","first-page":"S1","article-title":"Introduction and overview of radiofrequency treatments in aesthetic dermatology","volume":"21","author":"Delgado AR","year":"2022","journal-title":"J Cosmet Dermatol"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/jocd.13206"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/jocd.12776"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.12788\/j.sder.0016"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.sder.2009.11.003"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.23295"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-3083.2009.03355.x"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-3083.2009.03254.x"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/exd.14363"},{"key":"e_1_2_11_14_1","first-page":"19","article-title":"The need to report effect size estimates revisited. 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