{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T03:07:55Z","timestamp":1783652875496,"version":"3.55.0"},"reference-count":26,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2024,9,17]],"date-time":"2024-09-17T00:00:00Z","timestamp":1726531200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2024,9,17]],"date-time":"2024-09-17T00:00:00Z","timestamp":1726531200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82302810"],"award-info":[{"award-number":["82302810"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Cosmetic Dermatology"],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>\n                      The field of cosmetic filler injection has experienced rapid development over the past two decades, especially in facial augmentation utilizing hyaluronic acid (HA) fillers. Gram\u2010negative bacteria are found to be the main pathogens of infective nodules after HA injection. The occurrence of cutaneous infections attributed to\n                      <jats:italic>Serratia marcescens<\/jats:italic>\n                      is exceedingly rare and predominantly noted in patients with compromised immune systems.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>\n                      To summarize the clinical features, diagnosis, and treatment of subcutaneous infection caused by\n                      <jats:italic>Serratia marcescens<\/jats:italic>\n                      following hyaluronic acid injection.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Patients\/Methods<\/jats:title>\n                    <jats:p>\n                      A rare case of cutaneous\n                      <jats:italic>Serratia marcescens<\/jats:italic>\n                      infection following hyaluronic acid injection was presented. A comprehensive review of the published literature describing the management of skin infection caused by\n                      <jats:italic>S. marcescens<\/jats:italic>\n                      in immunocompetent patients was then conducted, which encompassed three case series and eight case reports published between 1999 and 2017. Data extraction included information on authors, gender, age, signs and symptoms, previous treatment, corresponding management strategies, and follow\u2010up duration.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      <jats:italic>Serratia marcescens<\/jats:italic>\n                      were isolated in abscesses (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u20096, 35.29%), painful nodules (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u20092, 11.76%), ulcers (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u20096, 35.29%), and others (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u20093, 17.65%). In cases providing salvage plans (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200911), quinolones were shown to be the most effective antibiotics for salvage, with eight full recoveries (72.73%), and trimethoprim\u2010sulfamethoxazole was the second most useful antibiotic (18.18%).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>\n                      With the help of pathogen examination and drug\u2010sensitive tests, sensitive aminoglycosides, quinolone (especially moxifloxacin), or TMP\u2010SMX for at least 2\u2009weeks can be considered as the first\u2010line treatment of late subcutaneous infection caused by\n                      <jats:italic>Serratia marcescens<\/jats:italic>\n                      following hyaluronic acid injection.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jocd.16571","type":"journal-article","created":{"date-parts":[[2024,9,17]],"date-time":"2024-09-17T13:49:22Z","timestamp":1726580962000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Late Subcutaneous Infection Caused by\n                    <i>Serratia marcescens<\/i>\n                    Following Hyaluronic Acid Injection: A Case Report and Systemic Review"],"prefix":"10.1111","volume":"24","author":[{"given":"Yihan","family":"Zhang","sequence":"first","affiliation":[{"name":"Department of Plastic and Reconstructive Surgery Peking University Shenzhen Hospital  Shenzhen Guangdong P.R. China"},{"name":"Shantou University Medical College  Shantou P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yansi","family":"Lyu","sequence":"additional","affiliation":[{"name":"Department of Dermatology Shenzhen University General Hospital  Shenzhen Guangdong P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tingyin","family":"Lin","sequence":"additional","affiliation":[{"name":"Department of Plastic and Reconstructive Surgery Peking University Shenzhen Hospital  Shenzhen Guangdong P.R. China"},{"name":"Shantou University Medical College  Shantou P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luotai","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Plastic and Reconstructive Surgery Peking University Shenzhen Hospital  Shenzhen Guangdong P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhuolin","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Plastic and Reconstructive Surgery Peking University Shenzhen Hospital  Shenzhen Guangdong P.R. China"},{"name":"Shantou University Medical College  Shantou P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanting","family":"Ou","sequence":"additional","affiliation":[{"name":"Department of Plastic and Reconstructive Surgery Peking University Shenzhen Hospital  Shenzhen Guangdong P.R. China"},{"name":"Shantou University Medical College  Shantou P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiangwen","family":"Xu","sequence":"additional","affiliation":[{"name":"Department of Plastic and Reconstructive Surgery Shenzhen Xinhua Hospital  Shenzhen P.R. 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China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-2219-4656","authenticated-orcid":false,"given":"Dandan","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Plastic and Reconstructive Surgery Peking University Shenzhen Hospital  Shenzhen Guangdong P.R. 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