{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T15:11:35Z","timestamp":1789053095160,"version":"build-2803163510"},"reference-count":37,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2024,9,16]],"date-time":"2024-09-16T00:00:00Z","timestamp":1726444800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2024,9,16]],"date-time":"2024-09-16T00:00:00Z","timestamp":1726444800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Cosmetic Dermatology"],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Poly\u2010D,L\u2010lactic acid (PDLLA) is used for tear trough rejuvenation but can cause complications like nodular reactions. This report describes using a radiofrequency device to manage these nodules.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case Presentation<\/jats:title>\n                    <jats:p>A 42\u2010year\u2010old woman developed firm, non\u2010inflammatory nodules 3\u2009weeks after receiving PDLLA (Juvelook) injections in the tear trough area. The nodules were firm and not associated with erythema or tenderness.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Intervention<\/jats:title>\n                    <jats:p>The monopolar radiofrequency device was used directly on the nodules with 150 shots at an energy level 115 J, 28.75 J\/cm\u00b2. The treatment resulted in complete resolution of the nodules within 24 hours.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The radiofrequency treatment effectively resolved the nodular reaction without recurrence, highlighting the device's compatibility with the unique structure of Juvelook's PDLLA.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Radiofrequency therapy is effective for managing nodular reactions following PDLLA injections. Further research is needed to optimise protocols and improve the safety of biostimulator treatments in cosmetic procedures.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jocd.16575","type":"journal-article","created":{"date-parts":[[2024,9,16]],"date-time":"2024-09-16T08:20:25Z","timestamp":1726474825000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Energy\u2010Based Device Management of Nodular Reaction Following Poly\u2010D, L\u2010Lactic Acid Injection for Tear Trough Rejuvenation"],"prefix":"10.1111","volume":"24","author":[{"given":"Suk Bae","family":"Seo","sequence":"first","affiliation":[{"name":"SeoAhSong Dermatologic Clinic  Seoul Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jovian","family":"Wan","sequence":"additional","affiliation":[{"name":"Asia\u2010Pacific Aesthetic Academy  Hong Kong Hong Kong"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5572-1364","authenticated-orcid":false,"given":"Kyu\u2010Ho","family":"Yi","sequence":"additional","affiliation":[{"name":"Division in Anatomy and Developmental Biology, Department of Oral Biology Human Identification Research Institute, BK21 FOUR Project, Yonsei University College of Dentistry  Seoul Korea"},{"name":"Maylin Clinic (Apgujeong)  Seoul Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,9,16]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/srt.13762"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.3390\/antiox12061204"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/PRS.0000000000001247"},{"issue":"1","key":"e_1_2_8_5_1","first-page":"5","article-title":"Injectable Poly\u2010D, L\u2010Lactic Acid in Facial Rejuvenation: Three Case Reports2020","volume":"4","author":"Lin J.\u2010Y.","year":"2020","journal-title":"Journal of Cosmetology"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.20517\/2347\u20109264.2019.23"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/jbm.820270904"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1093\/asj\/sjy012"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1177\/1090820X10391213"},{"issue":"6","key":"e_1_2_8_10_1","first-page":"759","article-title":"Injectable Poly\u2010L\u2010Lactic Acid: Understanding Its Use in the Current Era","volume":"15","author":"Lorenc Z. 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