{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,4]],"date-time":"2026-07-04T17:39:45Z","timestamp":1783186785874,"version":"3.54.6"},"reference-count":12,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2024,10,24]],"date-time":"2024-10-24T00:00:00Z","timestamp":1729728000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2024,10,24]],"date-time":"2024-10-24T00:00:00Z","timestamp":1729728000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Cosmetic Dermatology"],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>The \u201c4.3\u201d technique is a hybrid lip augmentation approach that combines the aesthetic benefits of the vertical\u2010lip technique with the fewer entry points of the retrograde linear technique. This method aims to create natural\u2010looking, harmonious, and defined lips using hyaluronic acid (HA)\u2010based fillers, to enhance volume and contour.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>The objective of this study is to evaluate the effectiveness, safety, and reproducibility of the \u201c4.3\u201d technique in achieving natural lip augmentation with minimal filler volume and reduced injections. This technique is applied to improve the shape and volume of the lips while minimizing the risk of complications.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Patients\/Methods<\/jats:title>\n                    <jats:p>The technique was applied to male and female patients with standard anatomical features who desired subtle enhancements in lip contour, projection, and volume. The procedure involved four injections in the upper lip and three in the lower lip, using a combination of retrograde linear and vertical techniques. A total of 0.7\u2009mL of HA filler were used for each patient.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The \u201c4.3\u201d technique achieved consistent and aesthetically pleasing results across all patients, with improvements in lip volume, shape, and definition. The reduced number of injections minimized discomfort and risk of vascular complications. The use of Tri\u2010Hyal technology contributed to smooth, plump lips with harmonious proportions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The \u201c4.3\u201d technique is a standardized, intuitive, and reproducible method suitable for most patients, regardless of sex. It allows for natural\u2010looking lip augmentation using a reduced volume of filler and fewer injections, making it a safe and effective option for enhancing lip aesthetics.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jocd.16601","type":"journal-article","created":{"date-parts":[[2024,10,24]],"date-time":"2024-10-24T06:29:51Z","timestamp":1729751391000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["The \u201c4.3,\u201d A New Filler Lips Technique"],"prefix":"10.1111","volume":"24","author":[{"given":"Francesco","family":"Castellaneta","sequence":"first","affiliation":[{"name":"Department of Plastic and Reconstructive Surgery Basilicata Oncology Reference Center IRCCS\u2010CROB  Rionero In Vulture Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mariagiovanna","family":"Lombardi","sequence":"additional","affiliation":[{"name":"Department of Plastic and Reconstructive Surgery Federico II University of Naples  Naples Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Santolo","family":"D'Antonio","sequence":"additional","affiliation":[{"name":"Department of Plastic and Reconstructive Surgery Federico II University of Naples  Naples Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tommaso","family":"Fabrizio","sequence":"additional","affiliation":[{"name":"Department of Plastic and Reconstructive Surgery Basilicata Oncology Reference Center IRCCS\u2010CROB  Rionero In Vulture Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,10,24]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.sder.2006.06.011"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.coms.2021.01.004"},{"issue":"1","key":"e_1_2_8_4_1","first-page":"E61","article-title":"Lip Augmentation Using Hyaluronic Acid Filler and a 4\u2010mm Needle: A Safer, More Natural, and Predictable Approach","volume":"14","author":"Walker L.","year":"2021","journal-title":"Journal of Clinical and Aesthetic Dermatology"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.36849\/JDD.6304"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.4103\/0974\u20102077.167269"},{"key":"e_1_2_8_7_1","volume-title":"StatPearls [Internet]","author":"Nguyen J. D.","year":"2023"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/PRS.0000000000000858"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1093\/asj\/sjz028"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/PRS.0000000000003244"},{"key":"e_1_2_8_11_1","first-page":"109","volume-title":"Soft Tissue Augmentation","author":"Carruthers J.","year":"2006"},{"issue":"7","key":"e_1_2_8_12_1","first-page":"764","article-title":"Small Gel Particle Hyaluronic Acid Injection Technique for Lip Augmentation","volume":"12","author":"Smith S. R.","year":"2013","journal-title":"Journal of Drugs in Dermatology"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.sap.0000168292.69753.73"}],"container-title":["Journal of Cosmetic Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jocd.16601","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/jocd.16601","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jocd.16601","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,17]],"date-time":"2026-03-17T14:39:29Z","timestamp":1773758369000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jocd.16601"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,10,24]]},"references-count":12,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2025,1]]}},"alternative-id":["10.1111\/jocd.16601"],"URL":"https:\/\/doi.org\/10.1111\/jocd.16601","archive":["Portico"],"relation":{},"ISSN":["1473-2130","1473-2165"],"issn-type":[{"value":"1473-2130","type":"print"},{"value":"1473-2165","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,10,24]]},"assertion":[{"value":"2024-03-25","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-09-11","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-10-24","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e16601"}}