{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T21:51:36Z","timestamp":1791496296545,"version":"4.3.4"},"reference-count":17,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2024,11,27]],"date-time":"2024-11-27T00:00:00Z","timestamp":1732665600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2024,11,27]],"date-time":"2024-11-27T00:00:00Z","timestamp":1732665600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Cosmetic Dermatology"],"published-print":{"date-parts":[[2025,2]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Eyebrows significantly influence facial aesthetics and are often linked to attractiveness and personality. Eyebrow loss and alopecia impact physical and psychological well\u2010being. Several treatments, including mesotherapy (MT), aim to enhance eyebrow density and quality. Despite the availability of MT for hair growth, its application in eyebrow revitalization is less explored.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>This study evaluates clients' perceptions and satisfaction with eyebrow MT (EB MT) using AQ skin solutions' growth factor\u2010based MT cocktail serum.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Patients\/Methods<\/jats:title>\n                    <jats:p>Thirty\u2010two healthy women (ages 21\u201355) with thin or weakened eyebrows underwent three EB MT sessions spaced 2\u20134\u2009weeks apart. Exclusion criteria included chronic diseases, allergies, and conditions like pregnancy. Each session lasted about 40\u2009min, and \u201cpoint by point\u201d and \u201cnappage\u201d techniques were employed. Satisfaction and pain levels were assessed through a Numeric Rating Scale for Satisfaction (NRSS) and Pain scale, while photographic analysis and the Global Aesthetic Improvement Scale (GAIS) evaluated effectiveness.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The average GAIS score was 8.28, while the NRSS satisfaction score was 8.06. Pain levels were moderately low, averaging 4.0. A high majority (90.6%) were satisfied and willing to continue treatment, with 100% recommending EB MT to others. Notable improvements in overall appearance were reported by participants.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>EB MT demonstrated high satisfaction and low pain levels, with significant improvements in eyebrow density and appearance. This treatment is a practical option for eyebrow enhancement with a strong safety profile, motivating further clinical application.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jocd.16699","type":"journal-article","created":{"date-parts":[[2024,11,28]],"date-time":"2024-11-28T01:55:25Z","timestamp":1732758925000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Assessment of Clients' Perceptions and Satisfaction With Eyebrow Mesotherapy Treatment"],"prefix":"10.1111","volume":"24","author":[{"ORCID":"https:\/\/orcid.org\/0009-0003-6558-1301","authenticated-orcid":false,"given":"Krenar","family":"Dobroshi","sequence":"first","affiliation":[{"name":"Alma Mater Europaea College of Medical Sciences \u201cRezonanca\u201d  Prishtina Albania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marija Glavash","family":"Dodov","sequence":"additional","affiliation":[{"name":"The Saints Cyril and Methodius University Faculty of Pharmacy  Skopje North Macedonia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maja Simonovska","family":"Crcarevska","sequence":"additional","affiliation":[{"name":"The Saints Cyril and Methodius University Faculty of Pharmacy  Skopje North Macedonia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Renata Slaveska","family":"Raichki","sequence":"additional","affiliation":[{"name":"The Saints Cyril and Methodius University Faculty of Pharmacy  Skopje North Macedonia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Selvete","family":"Shuleta\u2010Qehaja","sequence":"additional","affiliation":[{"name":"Alma Mater Europaea College of Medical Sciences \u201cRezonanca\u201d  Prishtina Albania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Blerim","family":"Krasniqi","sequence":"additional","affiliation":[{"name":"Alma Mater Europaea College of Medical Sciences \u201cRezonanca\u201d  Prishtina Albania"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,11,27]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/ijd.12362"},{"issue":"1","key":"e_1_2_8_3_1","first-page":"s12","article-title":"Nguyen MD the Biology, Structure, and Function of Eyebrow Hair","volume":"13","author":"Jennifer V.","year":"2014","journal-title":"Journal of Drugs in Dermatology"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.2466\/PR0.67.7.775-778"},{"issue":"1","key":"e_1_2_8_5_1","first-page":"1","article-title":"Alopecia areata","volume":"3","author":"Pratt Herbert C.","year":"2017","journal-title":"Nature Reviews. Disease Primers"},{"key":"e_1_2_8_6_1","first-page":"59","article-title":"What Is Mesotherapy?","volume":"46","author":"Pistor M.","year":"1976","journal-title":"Le Chirurgien\u2010Dentiste de France"},{"issue":"6","key":"e_1_2_8_7_1","first-page":"682","article-title":"Mesotherapy, Definition, Rationale and Clinical Role: A Consensus Report From the Italian Society of Mesotherapy","volume":"15","author":"Mammucari M.","year":"2011","journal-title":"European Review for Medical and Pharmacological Sciences"},{"key":"e_1_2_8_8_1","first-page":"53","article-title":"Mesotherapy and Cellulite","volume":"4","author":"Leibaschoff G.","year":"2006","journal-title":"American Journal of Mesotherapy"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.PRS.0000162227.94032.ED"},{"key":"e_1_2_8_10_1","first-page":"21","article-title":"French Mesotherapy for the Treatment of Pain","volume":"15","author":"Adelson H.","year":"2005","journal-title":"American Journal of Mesotherapy"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1155\/2018\/6513049"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.5114\/ada.2022.118996"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-4632.2011.05184.x"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.4172\/2471-9323.1000104"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.23252"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10103-017-2232-8"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1248\/bpb.b16-00113"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13555-012-0018-2"}],"container-title":["Journal of Cosmetic Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jocd.16699","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/jocd.16699","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jocd.16699","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T21:44:23Z","timestamp":1791495863000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jocd.16699"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,11,27]]},"references-count":17,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2025,2]]}},"alternative-id":["10.1111\/jocd.16699"],"URL":"https:\/\/doi.org\/10.1111\/jocd.16699","archive":["Portico"],"relation":{},"ISSN":["1473-2130","1473-2165"],"issn-type":[{"value":"1473-2130","type":"print"},{"value":"1473-2165","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,11,27]]},"assertion":[{"value":"2024-06-15","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-11-13","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-11-27","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e16699"}}