{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T21:51:47Z","timestamp":1791496307642,"version":"4.3.4"},"reference-count":14,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2025,2,12]],"date-time":"2025-02-12T00:00:00Z","timestamp":1739318400000},"content-version":"vor","delay-in-days":11,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,2,1]],"date-time":"2025-02-01T00:00:00Z","timestamp":1738368000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Cosmetic Dermatology"],"published-print":{"date-parts":[[2025,2]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Rhinoplasty is a prominent procedure in facial aesthetics, but extended surgical downtime remains its significant limitation. Nonsurgical rhinoplasty has gained popularity as an alternative, offering significant aesthetic improvements with minimal downtime. This study evaluates the clinical efficacy and safety of three nonsurgical rhinoplasty techniques combined, including hyaluronic acid (HA) filler, botulinum toxin type A (BTX), and barbed lifting threads.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A total of 85 patients were included into three groups: 63 subjects received HA filler and BTX injections, 9 subjects received barbed threads followed by BTX injections, and 13 received threads followed by HA filler and BTX injections. Patients assessed their satisfaction 1\u2009month and a year posttreatment as well as adverse effects 48\u2009h and 1\u2009week after treatment using FACE\u2010Q questionnaire for nose.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Both 1\u2009month and a year after treatment, the triple combination of barbed threads with HA filler and BTX demonstrated superior nose FACE\u2010Q scores compared to the two other groups, showing highest patient satisfaction and minimal efficacy decay over time. No significant difference in FACE\u2010Q scores was observed between the two groups receiving HA filler\u2009+\u2009BTX and barbed threads\u2009+\u2009BTX at either 1\u2009month or a year posttreatment. Adverse effects were reported by subjects in all three groups 48\u2009h posttreatment and completely resolved by 1\u2009week after treatment.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Combining nonsurgical rhinoplasty techniques\u2014such as lifting threads, HA fillers, and botulinum toxin\u2014can deliver effective aesthetic improvements with minimal downtime. Among these, the triple combination of HA filler, BTX, and lifting threads results in the highest and most sustained patient satisfaction, lasting no less than 1 year.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jocd.70047","type":"journal-article","created":{"date-parts":[[2025,2,12]],"date-time":"2025-02-12T06:20:20Z","timestamp":1739341220000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Nasal Reshaping Using Barbed Threads Combined With Hyaluronic Acid Filler and Botulinum Toxin A"],"prefix":"10.1111","volume":"24","author":[{"given":"G.","family":"Ziade","sequence":"first","affiliation":[{"name":"Department of Otolaryngology\u2014Head and Neck Surgery Lebanese American University School of Medicine  Beirut Lebanon"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Saade","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2014Head and Neck Surgery Lebanese American University School of Medicine  Beirut Lebanon"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"Daou","sequence":"additional","affiliation":[{"name":"Department of Anesthesia American University of Beirut Medical Center  Beirut Lebanon"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"Karam","sequence":"additional","affiliation":[{"name":"Faculty of Medicine Holy Spirit University of Kaslik  Jounieh Lebanon"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Bendito","sequence":"additional","affiliation":[{"name":"Martina Children's Hospital  Stockholm Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Tsintsadze","sequence":"additional","affiliation":[{"name":"Faculty of Medicine BAU International University Batumi  Batumi Georgia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,2,12]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/asj\/sjad295"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1093\/asjof\/ojac035"},{"key":"e_1_2_10_4_1","unstructured":"B. S.RaggioandJ.Asaria \u201cFiller Rhinoplasty \u201dinStatPearls[Internet] (StatPearls Publishing 2024) https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK554581\/."},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1093\/asjof\/ojab010"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00266\u2010023\u201003386\u2010z"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00266\u2010018\u20101279\u20107"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/jocd.15669"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1055\/s\u20102003\u201043162"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1177\/1090820X10369157"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1080\/14764172.2017.1418509"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/DSS.0000000000002146"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1097\/GOX.0000000000001967"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/jocd.15885"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/GOX.0000000000004907"}],"container-title":["Journal of Cosmetic Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jocd.70047","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/jocd.70047","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jocd.70047","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T21:43:45Z","timestamp":1791495825000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jocd.70047"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,2]]},"references-count":14,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2025,2]]}},"alternative-id":["10.1111\/jocd.70047"],"URL":"https:\/\/doi.org\/10.1111\/jocd.70047","archive":["Portico"],"relation":{},"ISSN":["1473-2130","1473-2165"],"issn-type":[{"value":"1473-2130","type":"print"},{"value":"1473-2165","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,2]]},"assertion":[{"value":"2024-10-10","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-01-31","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-02-12","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70047"}}