{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T21:51:55Z","timestamp":1791496315237,"version":"4.3.4"},"reference-count":25,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2025,2,12]],"date-time":"2025-02-12T00:00:00Z","timestamp":1739318400000},"content-version":"vor","delay-in-days":11,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,2,1]],"date-time":"2025-02-01T00:00:00Z","timestamp":1738368000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Cosmetic Dermatology"],"published-print":{"date-parts":[[2025,2]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>The lip augmentation market is projected to reach a value of 11.6\u2009billion USD by 2030. Hyaluronic acid (HA) fillers are the most common type due to biocompatibility and reversibility. However, there has been an increase in alternative procedures, such as the \u201clip flip,\u201d involving the injection of botulinum neurotoxin A (BoNT\u2010A) into the superior orbicularis oris muscle.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>The purpose of this study is to review the current literature and evaluate the general public interest in dermal lip fillers compared to supralabial BoNT\u2010A injections over the past decade.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>The Google Trends database was used to collect relative monthly search volume for the terms \u201clip filler\u201d and \u201clip flip\u201d over a decade\u2010long period (January 1, 2014\u2013January 1, 2024). Google Trends data is automatically normalized with a value of 100 indicating maximal search volume and 1 indicating minimal search volume.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Search volume for lip filler and lip flip increased similarly from 2014 to 2024. Lip filler was consistently more searched and had an average 75% increase in relative search volume per month. Meanwhile, \u201clip flip\u201d had, on average, a 33% increase in search volume per month.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Although lip filler was more frequently inquired about than \u201clip flip,\u201d the latter increased in popularity over time, reaffirming its popularity as a potential alternative to lip filler. Superior obicularis oris BoNT\u2010A injections are rising in popularity and may be a valuable option for patients seeking cosmesis with hesitation toward dermal fillers.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jocd.70048","type":"journal-article","created":{"date-parts":[[2025,2,12]],"date-time":"2025-02-12T05:28:41Z","timestamp":1739338121000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Lip Filler Versus \u201cLip Flip\u201d: Longitudinal Public Interest and a Brief Review of Literature"],"prefix":"10.1111","volume":"24","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-3488-0389","authenticated-orcid":false,"given":"Raika","family":"Bourmand","sequence":"first","affiliation":[{"name":"Anne Burnett Marion School of Medicine Texas Christian University  Fort Worth Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4678-9962","authenticated-orcid":false,"given":"Sofia E.","family":"Olsson","sequence":"additional","affiliation":[{"name":"Anne Burnett Marion School of Medicine Texas Christian University  Fort Worth Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shirin","family":"Soleimani","sequence":"additional","affiliation":[{"name":"Anne Burnett Marion School of Medicine Texas Christian University  Fort Worth Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arman","family":"Fijany","sequence":"additional","affiliation":[{"name":"Anne Burnett Marion School of Medicine Texas Christian University  Fort Worth Texas USA"},{"name":"Vanderbilt University Medical Center  Nashville Tennessee USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,2,12]]},"reference":[{"key":"e_1_2_10_2_1","unstructured":"Grandview Research \u201cLip Augmentation Market Size to Reach $11.61Bn By 2030 \u201d(2023) https:\/\/www.grandviewresearch.com\/press\u2010release\/global\u2010lip\u2010augmentation\u2010market."},{"key":"e_1_2_10_3_1","unstructured":"American Board of Facial Cosmetic Surgery \u201cHeard About the BOTOX\u00ae Lip Flip? Here Are the Pros & Cons \u201d(2021) ambrdfcs.org\/blog\/pros\u2010cons\u2010botox\u2010lip\u2010flip\/."},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.2147\/CCID.S420921"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpra.2022.05.011"},{"key":"e_1_2_10_6_1","unstructured":"FDA \u201cDermal Fillers (Soft Tissue Fillers) \u201d(2021) www.fda.gov\/medical\u2010devices\/aesthetic\u2010cosmetic\u2010devices\/dermal\u2010fillers\u2010soft\u2010tissue\u2010filler."},{"key":"e_1_2_10_7_1","unstructured":"American Board of Cosmetic Energy \u201cInjectable Fillers Guide \u201d(2014) https:\/\/www.americanboardcosmeticsurgery.org\/procedure\u2010learning\u2010center\/non\u2010surgical\/injectable\u2010fillers\u2010guide\/."},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.53513"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1055\/s\u20100029\u20101220645"},{"key":"e_1_2_10_10_1","unstructured":"West County Plastic Surgeons \u201cA Brief History of Lip Injections \u201d(2016) wustl.edu\/blog\/2016\/08\/22\/a\u2010brief\u2010history\u2010of\u2010lip\u2010injections\/."},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/jocd.12861"},{"key":"e_1_2_10_12_1","unstructured":"FDA \u201cDermal Filler Do's and Don'ts for Wrinkles Lips and More \u201d(2022) www.fda.gov\/consumers\/consumer\u2010updates\/dermal\u2010filler\u2010dos\u2010and\u2010donts\u2010wrinkles\u2010lips\u2010and\u2010more."},{"key":"e_1_2_10_13_1","unstructured":"American Society of Plastic Surgeons \u201cDermal Fillers Cost \u201d(2025) www.plasticsurgery.org\/cosmetic\u2010procedures\/dermal\u2010fillers\/cost."},{"key":"e_1_2_10_14_1","unstructured":"D.Shira \u201cConsidering a Lip Flip? Here's Why Experts Say Proceed With Caution \u201d(2024) www.forbes.com\/sites\/dahvishira\/2024\/02\/21\/considering\u2010a\u2010lip\u2010flip\u2010heres\u2010why\u2010experts\u2010say\u2010proceed\u2010with\u2010caution\/."},{"key":"e_1_2_10_15_1","unstructured":"M.Freeman \u201cLip Flips May Have Been Trending on TikTok But Is it the Right Choice for You?\u201d(2022) www.plasticsurgery.org\/news\/articles\/lip\u2010flips\u2010may\u2010have\u2010been\u2010trending\u2010on\u2010tiktok\u2010but\u2010is\u2010it\u2010the\u2010right\u2010choice\u2010for\u2010you."},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.4103\/0974\u20102077.99451"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.2196\/54217"},{"key":"e_1_2_10_18_1","unstructured":"Kinsta \u201cSearch Engine Market Share: Who's Leading the Race in 2022 \u201d(2022) kinsta.com\/search\u2010engine\u2010market\u2010share\/."},{"key":"e_1_2_10_19_1","unstructured":"Cosmetic Plastic Surgery Statistics \u201cCosmetic Procedure Trends Cosmetic Surgical Procedures \u201d(2017)."},{"key":"e_1_2_10_20_1","unstructured":"American Society of Plastic SurgeonsandK.Clark \u201cFour Reasons a Person May Want Lip Filler \u201d(2021) www.plasticsurgery.org\/news\/articles\/four\u2010reasons\u2010a\u2010person\u2010may\u2010want\u2010lip\u2010filler."},{"issue":"7","key":"e_1_2_10_21_1","first-page":"26","article-title":"Evaluation of Current Literature on Complications Secondary to Lip Augmentation Following Dermal Filler Injection","volume":"16","author":"Diwan Z.","year":"2023","journal-title":"Journal of Clinical and Aesthetic Dermatology"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/jocd.13731"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1097\/JW9.0000000000000126"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.1093\/asjof\/ojae019"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.1177\/000313481107700832"},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.1177\/0963662519865687"}],"container-title":["Journal of Cosmetic Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jocd.70048","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/jocd.70048","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jocd.70048","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T21:43:45Z","timestamp":1791495825000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jocd.70048"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,2]]},"references-count":25,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2025,2]]}},"alternative-id":["10.1111\/jocd.70048"],"URL":"https:\/\/doi.org\/10.1111\/jocd.70048","archive":["Portico"],"relation":{},"ISSN":["1473-2130","1473-2165"],"issn-type":[{"value":"1473-2130","type":"print"},{"value":"1473-2165","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,2]]},"assertion":[{"value":"2024-08-18","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-02-03","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-02-12","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70048"}}