{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,3]],"date-time":"2026-11-03T00:43:32Z","timestamp":1793666612381,"version":"4.5.1"},"reference-count":27,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2025,2,13]],"date-time":"2025-02-13T00:00:00Z","timestamp":1739404800000},"content-version":"vor","delay-in-days":12,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,2,1]],"date-time":"2025-02-01T00:00:00Z","timestamp":1738368000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Cosmetic Dermatology"],"published-print":{"date-parts":[[2025,2]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>\n                      Long linear scars in cross\u2010sectional regions can adversely affect facial aesthetics and functionality, leading to substantial psychological distress. Early intervention with carbon dioxide ablative fractional laser (CO\n                      <jats:sub>2<\/jats:sub>\n                      \u2010AFL) and 595\u2010nm pulsed dye laser (PDL) has shown promise in mitigating post\u2010surgical scarring. However, the effectiveness of this treatment for extensive facial scars across different areas remains unclear.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      We reviewed medical records of 39 patients with long scars from facial trauma between January 2022 and October 2023. Treatment commenced with two sessions of PDL and three sessions of CO\n                      <jats:sub>2<\/jats:sub>\n                      \u2010AFL 1\u2009week post\u2010suture removal. Outcomes were assessed using Antera 3D imaging and the Patient and Observer Scar Assessment Scale (POSAS 3.0). Quality of life improvements were measured using the Short Form\u201036 Health Survey (SF\u201036).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      All patients completed five sessions of laser treatment. Significant reductions were noted in Patient and Observer scores on the POSAS (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.05). Antera 3D analysis revealed substantial improvements in average roughness, depression depth, and elevation depth across facial regions. The significance of improvements in color variation, texture elevation span, melanin hyperconcentration, and hemoglobin hyperconcentration varied by area. Patients also showed significant improvements in SF\u201036 scores for physical role limitations, social functioning, and emotional well\u2010being compared to pre\u2010treatment levels (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.05).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>\n                      Early sequential treatment with PDL and CO\n                      <jats:sub>2<\/jats:sub>\n                      \u2010AFL effectively improves long scars in various facial areas.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jocd.70053","type":"journal-article","created":{"date-parts":[[2025,2,13]],"date-time":"2025-02-13T04:15:47Z","timestamp":1739420147000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Efficiency of Early Sequential Laser Treatment for Facial Linear Scars in Cross\u2010Sectional Regions"],"prefix":"10.1111","volume":"24","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-2689-7117","authenticated-orcid":false,"given":"Lei","family":"Guo","sequence":"first","affiliation":[{"name":"Department of Plastic and Reconstructive Surgery, Xijing Hospital Fourth Military Medical University  Xi'an China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ping","family":"Xue","sequence":"additional","affiliation":[{"name":"Department of Plastic and Reconstructive Surgery, Xijing Hospital Fourth Military Medical University  Xi'an 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