{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T21:51:55Z","timestamp":1791496315350,"version":"4.3.4"},"reference-count":15,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2025,2,20]],"date-time":"2025-02-20T00:00:00Z","timestamp":1740009600000},"content-version":"vor","delay-in-days":19,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,2,1]],"date-time":"2025-02-01T00:00:00Z","timestamp":1738368000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Cosmetic Dermatology"],"published-print":{"date-parts":[[2025,2]]},"abstract":"ABSTRACT<\/jats:title>\n \n Background<\/jats:title>\n \n With the popularization of laser therapy, an increasing number of patients are undergoing fractional CO\n 2<\/jats:sub>\n laser therapy. It is particularly important to exercise caution and accelerate wound healing after laser surgery.\n <\/jats:p>\n <\/jats:sec>\n \n Aims<\/jats:title>\n \n This study aimed to examine the clinical efficacy of moist wound healing after fractional CO\n 2<\/jats:sub>\n laser therapy.\n <\/jats:p>\n <\/jats:sec>\n \n Patients\/Methods<\/jats:title>\n \n A total of 15 individuals volunteered to undergo fractional CO\n 2<\/jats:sub>\n laser therapy. The facial skin was irradiated with a fractional CO\n 2<\/jats:sub>\n laser in the deep mode, with an energy of 15\u2009mJ\/cm\n 2<\/jats:sup>\n and a density of 5%. The left and right sides of the faces were considered the observation and control groups, respectively. After laser therapy, medical cold compress patches were applied on the skin in the control group once a day for approximately 10\u201315\u2009min, whereas erythromycin ophthalmic ointment was applied on the skin in the observation group 6 times daily for wound care. The wound healing time, duration of erythema, and occurrence of adverse reactions were monitored in both groups.\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n The observation and control groups received different nursing interventions. The time to regression of erythema and swelling was significantly shorter in the observation group than in the control group. In addition, the scab formed at the wound site was thinner, and shedding was faster in the observation group than in the control group. The Clinical Erythema Assessment score of the observation group was significantly lower than that of the control group (\n p<\/jats:italic>\n \u2009<\u20090.05). The wound healing time was 5.73\u2009\u00b1\u20090.70\u2009days in the observation group and 7.73\u2009\u00b1\u20090.72\u2009days in the control group, with the difference being statistically significant (\n p<\/jats:italic>\n \u2009<\u20090.05). After 30\u2009min and 12\u2009h of nursing intervention, the Visual Analog Scale score of the observation group was significantly lower than that of the control group (\n p<\/jats:italic>\n \u2009<\u20090.05). However, after 24\u2009h of treatment, neither group showed significant pain. Both groups showed varying degrees of acne, pustules, and exudation, which subsided within 7\u2009days. Furthermore, the control group had 2 cases of mild pigmentation, which resolved within 3\u2009months. Neither group experienced adverse reactions such as skin infection, depigmentation, or scar formation.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n \n Moist healing therapy can accelerate wound healing and reduce the duration of erythema and edema after fractional CO\n 2<\/jats:sub>\n laser therapy, demonstrating potential clinical application value.\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/jocd.70079","type":"journal-article","created":{"date-parts":[[2025,2,20]],"date-time":"2025-02-20T13:04:27Z","timestamp":1740056667000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Evaluation of the Therapeutic Efficacy of Moist Wound Healing After Fractional\n \n CO\n 2<\/sub>\n <\/scp>\n Laser Surgery"],"prefix":"10.1111","volume":"24","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1049-1416","authenticated-orcid":false,"given":"Qingmei","family":"Jin","sequence":"first","affiliation":[{"name":"Department of Dermatology Yanbian University Hospital Yanji China"},{"name":"Department of Medical Cosmetology Yanbian University Hospital Yanji China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3753-1297","authenticated-orcid":false,"given":"Richeng","family":"Dong","sequence":"additional","affiliation":[{"name":"Department of Dermatology Suzhou Mylike Cosmetic Hospital Suzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiahui","family":"Zhi","sequence":"additional","affiliation":[{"name":"Department of Dermatology Suzhou Mylike Cosmetic Hospital Suzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huimin","family":"Yin","sequence":"additional","affiliation":[{"name":"Department of Medical Cosmetology Yanbian University Hospital Yanji China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meilan","family":"Nan","sequence":"additional","affiliation":[{"name":"Department of Medical Cosmetology Yanbian University Hospital Yanji China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhehu","family":"Jin","sequence":"additional","affiliation":[{"name":"Department of Dermatology Yanbian University Hospital Yanji China"},{"name":"Department of Medical Cosmetology Yanbian University Hospital Yanji China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chenglong","family":"Jin","sequence":"additional","affiliation":[{"name":"Department of Dermatology Suzhou Mylike Cosmetic Hospital Suzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,2,20]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1039\/D0SM02245D"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/jocd.13335"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/DSS.0000000000001219"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/jocd.15298"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.12968\/jowc.2016.25.3.122"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1038\/193293a0"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1155\/2015\/316235"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.7150\/jca.21780"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1089\/wound.2012.0412"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.12968\/bjon.2016.25.20.S40"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/PRS.0000000000002633"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1089\/wound.2012.0381"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2015.08.013"},{"issue":"4","key":"e_1_2_11_15_1","first-page":"304","article-title":"Observation on the Effect of Liquid Paraffin as Adjuvant Therapy in Treating Residual Wounds of Patients With Severe Burns","volume":"36","author":"Wang J. J.","year":"2020","journal-title":"Zhonghua Shao Shang Za Zhi"},{"issue":"4","key":"e_1_2_11_16_1","first-page":"342","article-title":"Clinical Application of Cold Compress Facial Mask in Pain Management After Laser Therapy","volume":"18","author":"Lu W. T.","year":"2022","journal-title":"Journal of Tissue Engineering and Reconstructive Surgery"}],"container-title":["Journal of Cosmetic Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jocd.70079","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/jocd.70079","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jocd.70079","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T21:43:47Z","timestamp":1791495827000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jocd.70079"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,2]]},"references-count":15,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2025,2]]}},"alternative-id":["10.1111\/jocd.70079"],"URL":"https:\/\/doi.org\/10.1111\/jocd.70079","archive":["Portico"],"relation":{},"ISSN":["1473-2130","1473-2165"],"issn-type":[{"value":"1473-2130","type":"print"},{"value":"1473-2165","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,2]]},"assertion":[{"value":"2024-10-19","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-02-12","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-02-20","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70079"}}