{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T15:07:49Z","timestamp":1787497669477,"version":"build-2736575974"},"reference-count":23,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2025,4,9]],"date-time":"2025-04-09T00:00:00Z","timestamp":1744156800000},"content-version":"vor","delay-in-days":8,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100005762","name":"National Taiwan University Hospital","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005762","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007225","name":"Ministry of Science and Technology","doi-asserted-by":"publisher","award":["109\u20102314\u2010B\u2010002\u2010114\u2010MY3"],"award-info":[{"award-number":["109\u20102314\u2010B\u2010002\u2010114\u2010MY3"]}],"id":[{"id":"10.13039\/100007225","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007225","name":"Ministry of Science and Technology","doi-asserted-by":"publisher","award":["111\u20102314\u2010B\u2010002\u2010161"],"award-info":[{"award-number":["111\u20102314\u2010B\u2010002\u2010161"]}],"id":[{"id":"10.13039\/100007225","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007225","name":"Ministry of Science and Technology","doi-asserted-by":"publisher","award":["MOST 106\u20102314\u2010B\u2010002\u2010180\u2010MY3"],"award-info":[{"award-number":["MOST 106\u20102314\u2010B\u2010002\u2010180\u2010MY3"]}],"id":[{"id":"10.13039\/100007225","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Cosmetic Dermatology"],"published-print":{"date-parts":[[2025,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Lips are central to facial aesthetics, influencing overall balance and harmony. Ultrasound has become a key tool for assessing lip musculature and neurovascular structures, particularly in aesthetic filler injections. By enhancing precision and safety, ultrasound is valuable in procedures addressing age\u2010related lip changes, yet standardized scanning protocols remain underexplored.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>This review examined lip anatomy, summarized ultrasound applications in aesthetic procedures, introduced a structured scanning protocol, and highlighted its role in guiding filler injections.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A systematic search of PubMed, Scopus, Embase, and Web of Science was conducted up to August 1, 2024, using keywords related to ultrasound and lip anatomy. Studies involving human subjects or cadavers using ultrasound for lip assessment and injection guidance were included, whereas nonhuman studies, alternative imaging methods, and research unrelated to the lip region were excluded. Six studies met the criteria.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Ultrasound improves precision in lip injections by identifying key structures, including the superior and inferior labial arteries and the orbicularis oris muscle, reducing vascular risks. A structured scanning approach enhances procedural safety and efficacy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Ultrasound is a valuable tool in aesthetic lip procedures, improving accuracy and minimizing complications. Further research is needed to refine protocols and establish ultrasound as a standard practice in lip augmentation.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jocd.70164","type":"journal-article","created":{"date-parts":[[2025,4,9]],"date-time":"2025-04-09T04:05:52Z","timestamp":1744171552000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Lip Sonoanatomy and Relevance to Aesthetic Filler Injections: A Pictorial Review"],"prefix":"10.1111","volume":"24","author":[{"given":"Wei\u2010Ting","family":"Wu","sequence":"first","affiliation":[{"name":"Department of Physical Medicine and Rehabilitation National Taiwan University Hospital Bei\u2010Hu Branch  Taipei Taiwan"},{"name":"Department of Physical Medicine and Rehabilitation National Taiwan University College of Medicine  Taipei Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7558-5651","authenticated-orcid":false,"given":"Ke\u2010Vin","family":"Chang","sequence":"additional","affiliation":[{"name":"Department of Physical Medicine and Rehabilitation National Taiwan University Hospital Bei\u2010Hu Branch  Taipei Taiwan"},{"name":"Department of Physical Medicine and Rehabilitation National Taiwan University College of Medicine  Taipei Taiwan"},{"name":"Center for Regional Anesthesia and Pain Medicine Wang\u2010Fang Hospital, Taipei Medical University  Taipei Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ond\u0159ej","family":"Na\u0148ka","sequence":"additional","affiliation":[{"name":"Institute of Anatomy, Charles University, First Faculty of Medicine  Prague Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hsiang\u2010Chi","family":"Chang","sequence":"additional","affiliation":[{"name":"Department of Physical Medicine and Rehabilitation Taipei Hospital Ministry of Health and Welfare  New Taipei City Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vincenzo","family":"Ricci","sequence":"additional","affiliation":[{"name":"Physical and Rehabilitation Medicine Unit Luigi Sacco University Hospital, ASST Fatebenefratelli\u2010Sacco  Milan Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kamal","family":"Mezian","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation Medicine Charles University, First Faculty of Medicine and General University Hospital in Prague  Prague Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Levent","family":"\u00d6z\u00e7akar","sequence":"additional","affiliation":[{"name":"Department of Physical and Rehabilitation Medicine Hacettepe University Medical School  Ankara Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,4,9]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjps.2015.03.013"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.3390\/toxins14020101"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.3390\/diagnostics12071766"},{"issue":"7","key":"e_1_2_12_5_1","first-page":"E59","article-title":"Delayed\u2010Onset Nodules (DONs) and Considering Their Treatment Following Use of Hyaluronic Acid (HA) Fillers","volume":"14","author":"Convery C.","year":"2021","journal-title":"Journal of Clinical and Aesthetic Dermatology"},{"issue":"19","key":"e_1_2_12_6_1","first-page":"9043","article-title":"Perspectives and Challenges in Lip Rejuvenation: A Systematic Review","volume":"27","author":"Tabassum N.","year":"2023","journal-title":"European Review for Medical and Pharmacological Sciences"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/jocd.16393"},{"key":"e_1_2_12_8_1","volume-title":"Anatomy, Head and Neck, Lips","author":"Piccinin M. 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