{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T19:56:57Z","timestamp":1787169417293,"version":"build-2736575974"},"reference-count":30,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2025,4,28]],"date-time":"2025-04-28T00:00:00Z","timestamp":1745798400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,4,28]],"date-time":"2025-04-28T00:00:00Z","timestamp":1745798400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Cosmetic Dermatology"],"published-print":{"date-parts":[[2025,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Androgenetic alopecia (AGA) is the most common cause of hair loss globally, affecting millions of people, particularly men. Current treatments include FDA\u2010approved drugs and devices, but many patients experience side effects or suboptimal results. The niostem device is a new, wearable device that delivers low\u2010level electrical stimulation to promote hair growth. This pilot study aims to evaluate the efficacy and safety of the niostem device in male AGA patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A total of 21 male patients with AGA used the niostem device daily for 30\u2009min over 6\u2009months. Participants had not used any anti\u2010hair loss products within the 6\u2009months preceding the start of the study. Hair density, thickness, and terminal hair counts were assessed at baseline, 3\u2009months, and 6\u2009months using trichoscopic measurements. Patient\u2010reported outcomes were recorded, and adverse events were monitored.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The niostem device resulted in significant increases in hair count, with a 12% increase in total hair density at 3\u2009months and a 19.3% increase at 6\u2009months. Hair thickness also increased by 8.8% in 6\u2009months. Terminal hair density improved significantly over time, with visible hair growth observed in the participants. No adverse events were reported.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The niostem device demonstrated a significant increase in hair density and hair thickness in male AGA patients, with no adverse effects. Further large\u2010scale studies are warranted.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jocd.70202","type":"journal-article","created":{"date-parts":[[2025,4,29]],"date-time":"2025-04-29T02:55:12Z","timestamp":1745895312000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Novel Electrotrichogenic Device Promotes Hair Growth in Men With Androgenetic Alopecia: A Pilot Study"],"prefix":"10.1111","volume":"24","author":[{"given":"Samuel","family":"Jellard","sequence":"first","affiliation":[{"name":"Mane Biotech GmbH  Cologne Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephanie","family":"Moore","sequence":"additional","affiliation":[{"name":"Surrey Trichology Clinic  Surrey UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5881-3026","authenticated-orcid":false,"given":"Carlos 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