{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,8]],"date-time":"2026-04-08T16:08:12Z","timestamp":1775664492249,"version":"3.50.1"},"reference-count":17,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2025,5,26]],"date-time":"2025-05-26T00:00:00Z","timestamp":1748217600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Cosmetic Dermatology"],"published-print":{"date-parts":[[2025,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Lips are crucial to facial aesthetics, with fuller lips often deemed more attractive. This preference has led to increased demand for non\u2010surgical lip augmentation using dermal fillers. However, there is a gap in the literature regarding the identification and management of a particular anatomical variant colloquially known as \u201cM\u2010shaped lips\u201d, characterized by a central \u201cM\u201d configuration of the upper lip. This anatomical variant presents unique complexities. This study presents the first classification system for M\u2010shaped lips to guide safer, more predictable treatments.<\/jats:p><\/jats:sec><jats:sec><jats:title>Aims<\/jats:title><jats:p>To introduce the first classification system for M\u2010shaped lips, improving diagnostic accuracy, treatment strategies, and minimizing complications in cosmetic lip augmentation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A case series of nine patients aged 20\u201345 with M\u2010shaped lips seeking cosmetic augmentation were treated with Aliaxin LV, a hyaluronic acid filler, in multiple sessions. The proposed classification system was based on the angle between the vertical and horizontal midlines of the lips, including three grades: mild (\u2264\u200915\u00b0), moderate (16\u00b0\u201325\u00b0), and severe (&gt;\u200925\u00b0). Injection techniques and filler volumes were tailored according to patient classification using needles and cannulas for precise placement.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The classification system facilitated personalized treatments, resulting in satisfactory aesthetic outcomes without significant complications. All the patients showed improved lip symmetry and volume, with no instances of filler migration or vascular complications.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The findings suggest that this classification system can significantly improve cosmetic results and reduce risks in treatment. Larger studies with more diverse populations and extended follow\u2010up are needed to validate these findings.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jocd.70239","type":"journal-article","created":{"date-parts":[[2025,5,27]],"date-time":"2025-05-27T01:58:59Z","timestamp":1748311139000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Innovative Classification of M\u2010Shaped Lips for Enhanced Refill Outcomes: A Case Series"],"prefix":"10.1111","volume":"24","author":[{"given":"Dina Moctezuma","family":"Villalobos","sequence":"first","affiliation":[{"name":"Signature Clinics  Barcelona Spain"},{"name":"Aesthetic Medicine and Integral Rejuvenation Universidad Cat\u00f3lica de Valencia  Valencia Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,5,26]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.14639\/0392-100X-1511"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.15406\/jdc.2023.07.00226"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/DSS.0000000000002325"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcms.2015.03.032"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.3390\/diagnostics14141555"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.3390\/diagnostics14151640"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1093\/asj\/sjaa137"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/ca.23379"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.3390\/life15020315"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00266-021-02190-x"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/9781119046974.ch8"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.36849\/JDD.6304"},{"key":"e_1_2_8_14_1","first-page":"4","article-title":"Esperienze Dermatologiche\u2014Dermatological Experiences Case Report Real\u2010life Experience of a New Crosslinked Hyaluronic Acid Lip Filler Esperienza d'uso di un Nuovo Filler Labbra All'Acido Ialuronico Reticolato","volume":"22","author":"Zazzaron M.","year":"2020","journal-title":"Esperienze Dermatologiche"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.7573\/dic.2024-10-6"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/jocd.15749"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1177\/1090820X13484492"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.3390\/cosmetics11040144"}],"container-title":["Journal of Cosmetic Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jocd.70239","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,23]],"date-time":"2025-06-23T08:56:30Z","timestamp":1750668990000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jocd.70239"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,5,26]]},"references-count":17,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2025,6]]}},"alternative-id":["10.1111\/jocd.70239"],"URL":"https:\/\/doi.org\/10.1111\/jocd.70239","archive":["Portico"],"relation":{},"ISSN":["1473-2130","1473-2165"],"issn-type":[{"value":"1473-2130","type":"print"},{"value":"1473-2165","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,5,26]]},"assertion":[{"value":"2024-09-24","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-05-05","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-05-26","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70239"}}