{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,5]],"date-time":"2026-09-05T05:54:37Z","timestamp":1788587677284,"version":"build-2803163510"},"reference-count":32,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2025,7,16]],"date-time":"2025-07-16T00:00:00Z","timestamp":1752624000000},"content-version":"vor","delay-in-days":15,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Cosmetic Dermatology"],"published-print":{"date-parts":[[2025,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Acne is a common disorder of the pilosebaceous unit, resulting from increased sebum secretion and the colonization of <jats:italic>Propionibacterium<\/jats:italic>. Scarring is the most common consequence of acne and can significantly affect patients' quality of life.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Patients with moderate to severe facial acne scars who were referred to the dermatology clinic in 2023 were enrolled. All patients underwent endo\u2010radiofrequency subcision (Endo\u2010RF subcision) on both sides of the face, with platelet\u2010rich plasma (PRP) administered on one side only. Scarring was assessed using quantitative and qualitative measures based on the Goodman and Baron's global scarring grading system.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Ten patients (eight females and two males) completed the study. Although qualitative scores improved in both groups, no statistically significant difference was observed. There was no significant correlation in the percentage of recovery between the two study groups (Endo\u2010RF and PRP\u2009+\u2009Endo\u2010RF) before and after treatment. Evaluations of the quantitative scores for both groups showed considerable improvements in the number of acne scars. A strongly significant correlation was observed in both groups compared to baseline. Although the combination therapy group showed greater improvement in quantitative scar scores from baseline, the difference was not statistically significant.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Both Endo\u2010RF subcision and PRP combined with Endo\u2010RF subcision are safe and effective modalities for treating post\u2010acne scars. Although each method can improve acne scars, the combination therapy of Endo\u2010RF with PRP may yield more desirable results.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jocd.70345","type":"journal-article","created":{"date-parts":[[2025,7,17]],"date-time":"2025-07-17T03:15:46Z","timestamp":1752722146000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Optimizing Post\u2010Acne Scar Treatment: A Pilot Comparative Study of Endo\u2010Radiofrequency Subcision With and Without Platelet\u2010Rich Plasma"],"prefix":"10.1111","volume":"24","author":[{"given":"Najmeh","family":"Ahramiyanpour","sequence":"first","affiliation":[{"name":"Department of Dermatology Bushehr Faculty of Medicine, Bushehr University of Medical Sciences  Bushehr Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roxana","family":"Kaveh","sequence":"additional","affiliation":[{"name":"Guilan Road Trauma Research Center Trauma Institute, Guilan University of Medical Sciences  Rasht Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elaheh","family":"Lotfi","sequence":"additional","affiliation":[{"name":"Yoosefabad Skin and Hair Center  Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fatemeh","family":"Rastaghi","sequence":"additional","affiliation":[{"name":"Department of Dermatology Afzalipour Hospital, Afzalipour Faculty of Medicine, Kerman University of Medical Sciences  Kerman Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,7,16]]},"reference":[{"key":"e_1_2_12_2_1","volume-title":"Dermatology","author":"Bolognia J. 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