{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T11:58:54Z","timestamp":1788263934366,"version":"build-2803163510"},"reference-count":73,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2025,8,29]],"date-time":"2025-08-29T00:00:00Z","timestamp":1756425600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,8,29]],"date-time":"2025-08-29T00:00:00Z","timestamp":1756425600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Cosmetic Dermatology"],"published-print":{"date-parts":[[2025,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Alopecia encompasses a group of conditions that can significantly impact quality of life, especially among women and younger individuals. While pharmaceutical therapies remain the cornerstone of treatment, laser and light\u2010based therapies, especially low\u2010level light therapy (LLLT), offer promising noninvasive alternatives. LLLT uses specific wavelengths of light to stimulate hair follicle repair, prolong the hair growth phase, and promote regrowth. Recent advancements in at\u2010home devices and dual\u2010wavelength LED systems have expanded access to these therapies. This review explores the role of LLLT in treating alopecias, evaluating its mechanisms, efficacy, and clinical applications.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A PubMed search using terms related to alopecia and laser\/light therapy was conducted. Results were limited to English\u2010only articles from 2020 to 2025, excluding duplicates. Additional articles were identified through citation tracking. Studies not focused on light\u2010based therapies were excluded.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Of 403 articles identified, 63 were included based on relevance to alopecia or hair loss and light\u2010based therapy. Results were categorized by treatment modality and type of hair loss, with overlap between categories.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion<\/jats:title>\n                    <jats:p>This review highlights the growing role of LLLT as an adjunct or alternative treatment for various types of alopecia. In androgenetic alopecia, LLLT improves hair density and follicular responsiveness, with enhanced outcomes when combined with minoxidil or finasteride. For telogen effluvium, LLLT shows potential in prolonging the anagen phase and reducing shedding, although larger studies are needed. In alopecia areata, LLLT may promote regrowth by modulating immune responses and improving perifollicular microcirculation. Emerging data also support LLLT in lichen planopilaris and central centrifugal alopecia (CCCA), with case reports showing reduced inflammation and hair regrowth. Overall, LLLT offers a noninvasive, well\u2010tolerated option across alopecia subtypes, though standardized protocols and long\u2010term data remain limited.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jocd.70434","type":"journal-article","created":{"date-parts":[[2025,8,29]],"date-time":"2025-08-29T10:45:04Z","timestamp":1756464304000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["The Use of Light\u2010Based Therapies in the Treatment of Alopecia"],"prefix":"10.1111","volume":"24","author":[{"given":"Robert J.","family":"Vanaria","sequence":"first","affiliation":[{"name":"Center for Clinical and Cosmetic Research  Aventura Florida USA"},{"name":"Hackensack Meridian School of Medicine  Nutley New Jersey USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-5303-5850","authenticated-orcid":false,"given":"Aysham","family":"Chaudry","sequence":"additional","affiliation":[{"name":"Center for Clinical and Cosmetic Research  Aventura Florida USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8978-7932","authenticated-orcid":false,"given":"Mark S.","family":"Nestor","sequence":"additional","affiliation":[{"name":"Center for Clinical and Cosmetic Research  Aventura Florida USA"},{"name":"Department of Dermatology and Cutaneous Surgery University of Miami Miller School of Medicine Miami  Miami Florida USA"},{"name":"Division of Plastic Surgery, Department of Surgery University of Miami Miller School of Medicine Miami  Miami Florida USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,8,29]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.3238\/arztebl.2016.0377"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.3949\/ccjm.88a.20014"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365\u20102133.2006.07409.x"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/jocd.14537"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.331.7522.951"},{"issue":"1","key":"e_1_2_11_7_1","first-page":"41","article-title":"Low\u2010Level Laser (Light) Therapy (LLLT) in Skin: Stimulating, Healing, Restoring","volume":"32","author":"Avci P.","year":"2013","journal-title":"Seminars in Cutaneous Medicine and Surgery"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.22170"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.3109\/09546634.2013.832134"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40257\u2010013\u20100060\u20106"},{"key":"e_1_2_11_11_1","unstructured":"M. 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