{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T04:33:39Z","timestamp":1788150819139,"version":"build-2803163510"},"reference-count":14,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,1,19]],"date-time":"2026-01-19T00:00:00Z","timestamp":1768780800000},"content-version":"vor","delay-in-days":18,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Cosmetic Dermatology"],"published-print":{"date-parts":[[2026,1]]},"abstract":"ABSTRACT<\/jats:title>\n \n Background<\/jats:title>\n Hyaluronic acid (HA)\u2010based injectables are generally considered safe. However, short\u2010 and long\u2010term complications may occur.<\/jats:p>\n <\/jats:sec>\n \n Objective<\/jats:title>\n To evaluate complications related to soft\u2010tissue augmentation presented to the Department of Dermatology at a university hospital.<\/jats:p>\n <\/jats:sec>\n \n Materials and Methods<\/jats:title>\n A retrospective analysis was conducted using electronic medical records from January 2019 to January 2025. Adverse events related to HA\u2010based injectables, their management, and outcomes were identified and evaluated.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n Thirty\u2010one patients (mean age: 50.4\u2009years) were included in the analysis. Injections have been administered by cosmeticians (2\/31), nonmedical practitioners (2\/31), or individuals of unknown qualification. The most common complications were biofilm formation and chronic immune reactions, followed by abscesses, Tyndall effect, vascular occlusion, and filler migration. Over half of the products involved were either uncertified or of unknown origin.<\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n The findings highlight the need for qualified practitioners, careful product selection, and adherence to standardized techniques. Enhancing practitioner education, establishing evidence\u2010based protocols, and strengthening regulatory oversight are essential to ensure patient safety in aesthetic medicine.<\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/jocd.70582","type":"journal-article","created":{"date-parts":[[2026,1,20]],"date-time":"2026-01-20T07:51:28Z","timestamp":1768895488000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Complications of Dermal Injectables\u2014A Retrospective Study"],"prefix":"10.1111","volume":"25","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1258-6390","authenticated-orcid":false,"given":"Lynhda","family":"Nguyen","sequence":"first","affiliation":[{"name":"Department of Laser and Aesthetics, Department of Dermatology and Venereology University Medical\u2010Center Hamburg\u2010Eppendorf Hamburg Germany"},{"name":"Department of Dermatology and Venereology University Medical\u2010Center Hamburg\u2010Eppendorf Hamburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4679-7137","authenticated-orcid":false,"given":"Stefan W.","family":"Schneider","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Venereology University Medical\u2010Center Hamburg\u2010Eppendorf Hamburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ute","family":"Siemann\u2010Harms","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Venereology University Medical\u2010Center Hamburg\u2010Eppendorf Hamburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katharina","family":"Herberger","sequence":"additional","affiliation":[{"name":"Department of Laser and Aesthetics, Department of Dermatology and Venereology University Medical\u2010Center Hamburg\u2010Eppendorf Hamburg Germany"},{"name":"Department of Dermatology and Venereology University Medical\u2010Center Hamburg\u2010Eppendorf Hamburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,1,19]]},"reference":[{"key":"e_1_2_10_2_1","unstructured":"Surgeons ASoP. American Society of Plastic Surgeons \u201cReveals 2022's Most Sought\u2010After Procedures \u201d(2023) https:\/\/www.prnewswire.com\/news\u2010releases\/american\u2010society\u2010of\u2010plastic\u2010surgeons\u2010reveals\u20102022s\u2010most\u2010sought\u2010after\u2010procedures\u2010301938919.html#:~:text=Of%20the%20nearly%2023.7%20million Skin%20Resurfacing%20(3%2C322%2C292%20procedures)."},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.2147\/CCID.S276676"},{"key":"e_1_2_10_4_1","first-page":"S92","article-title":"Understanding, Avoiding, and Managing Dermal Filler Complications","volume":"34","author":"Cohen J. 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