{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,24]],"date-time":"2026-01-24T18:28:48Z","timestamp":1769279328686,"version":"3.49.0"},"reference-count":24,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,12,25]],"date-time":"2025-12-25T00:00:00Z","timestamp":1766620800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,12,25]],"date-time":"2025-12-25T00:00:00Z","timestamp":1766620800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Cosmetic Dermatology"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Autologous fat grafting is commonly used in cosmetic dermatology, but it can cause serious complications, including nontuberculous mycobacterial infections when done under unsterile conditions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case Presentation<\/jats:title>\n                    <jats:p>\n                      We report a 39\u2010year\u2010old woman who developed multiple discharging facial abscesses 1\u2009month after undergoing autologous fat grafting in an unauthorized cosmetic clinic. Initial empiric oral therapy with clarithromycin, minocycline, and rifampin failed, prompting intravenous antibiotic therapy. During the hospitalization, she developed loss of consciousness, seizure, cerebral edema, and cavernous sinus thrombosis, followed by corticosteroid\u2010induced adrenal suppression. When visiting our clinic, biopsy, PCR, and culture were performed, which confirmed infection with\n                      <jats:styled-content style=\"fixed-case\">\n                        <jats:italic>Mycobacterium chelonae<\/jats:italic>\n                      <\/jats:styled-content>\n                      (\n                      <jats:styled-content style=\"fixed-case\">\n                        <jats:italic>M. chelonae<\/jats:italic>\n                      <\/jats:styled-content>\n                      ) after prolonged multidrug therapy with intravenous amikacin, imipenem, linezolid, and clarithromycin, and abscess drainage; the infection resolved. At 6\u2009months of follow\u2010up, no recurrence was observed, although residual scarring persisted.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>\n                      This case highlights a rare and severe systemic complication of\n                      <jats:styled-content style=\"fixed-case\">\n                        <jats:italic>Mycobacterium chelonae<\/jats:italic>\n                      <\/jats:styled-content>\n                      infection following cosmetic fat grafting, underscoring the need for strict aseptic technique, awareness of regional antimicrobial resistance, and better regulation of aesthetic procedures.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jocd.70631","type":"journal-article","created":{"date-parts":[[2025,12,26]],"date-time":"2025-12-26T07:39:53Z","timestamp":1766734793000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Infection With\n                    <scp>\n                      <i>Mycobacterium chelonae<\/i>\n                    <\/scp>\n                    Following Autologous Facial Fat Grafting: A Case Report and Review of Literature"],"prefix":"10.1111","volume":"25","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4440-335X","authenticated-orcid":false,"given":"Ilad","family":"Alavi Darazam","sequence":"first","affiliation":[{"name":"Department of Infectious Diseases and Tropical Medicine, Loghman Hakim Hospital Shahid Beheshti University of Medical Sciences  Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mahdi","family":"Isazadeh","sequence":"additional","affiliation":[{"name":"Skin Research Center Shahid Beheshti University of Medical Sciences  Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4002-6953","authenticated-orcid":false,"given":"Shirin","family":"Zaresharifi","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases and Tropical Medicine, Loghman Hakim Hospital Shahid Beheshti University of Medical Sciences  Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Farahnaz","family":"Bidari","sequence":"additional","affiliation":[{"name":"Department of Pathology, Loghman Hakim Hospital Shahid Beheshti University of Medical Sciences  Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7947-8642","authenticated-orcid":false,"given":"Reza M.","family":"Robati","sequence":"additional","affiliation":[{"name":"Skin Research Center Shahid Beheshti University of Medical Sciences  Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,12,25]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/jocd.16028"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijid.2024.107259"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jctube.2023.100381"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/ddg.15321"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13256-022-03678-z"},{"issue":"3","key":"e_1_2_11_7_1","first-page":"46","article-title":"Nontuberculous Mycobacterial Infections After Aesthetic Procedures: Comparison of Clinical Features and Treatment","volume":"14","author":"Safe I. 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